DX-8951 Hydroxy-acid sodium

Cat. No.: HY-178239A Purity: 98.65%: Data Sheet
COA

SDS
Handling Instructions
FAQs
Technical Support

DX-8951 Hydroxy-acid sodium is a prodrug of phosphoramide. DX-8951 Hydroxy-acid sodium can effectively increase intracellular ATP levels. DX-8951 Hydroxy-acid sodium activates the AMPK signaling pathway by increasing the AMP/ATP ratio. DX-8951 Hydroxy-acid sodium can enhance mitochondrial function and antioxidant capacity while reducing reactive oxygen species (ROS) levels. DX-8951 Hydroxy-acid sodium has shown significant anti-aging and longevity effects in both human fibroblast and nematode models.

For research use only. We do not sell to patients.

DX-8951 Hydroxy-acid sodium Chemical Structure

Size	Stock	Quantity
Solid + Solvent (Highly Recommended)
10 mM * 1 mL in DMSO ready for reconstitution	In-stock	Estimated Time of Arrival: December 31
Solution
10 mM * 1 mL in DMSO	In-stock	Estimated Time of Arrival: December 31
Solid
5 mg	In-stock	Estimated Time of Arrival: December 31
10 mg	In-stock	Estimated Time of Arrival: December 31
25 mg	In-stock	Estimated Time of Arrival: December 31
50 mg	In-stock	Estimated Time of Arrival: December 31
100 mg	Get quote
200 mg	Get quote

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This product is a controlled substance and not for sale in your territory.

Customer Review

Based on 1 publication(s) in Google Scholar

Other Forms of DX-8951 Hydroxy-acid sodium:

DX-8951 Hydroxy-acid Get quote

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View All AMPK Isoform Specific Products:

View All Isoforms

NUAK1 NUAK2 AMPK AMPK α1β1γ1 AMPK α2β1γ1 AMPK α1β2γ1 AMPK α2β2γ1 BRSK1 BRSK2 HUNK AMPKα

Biological Activity
Purity & Documentation
Customer Review

Description

Molecular Weight

475.44

Formula

C₂₄H₂₃FN₃NaO₅

Appearance

Solid

SMILES

FC1=CC2=NC3=C(CN4C3=CC([C@@](C(O[Na])=O)(O)CC)=C(CO)C4=O)C([C@@H](N)CC5)=C2C5=C1C

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

-20°C, sealed storage, away from moisture and light

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)

Solvent & Solubility

In Vitro:

DMSO : 25 mg/mL (52.58 mM; Need ultrasonic and warming; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	2.1033 mL	10.5166 mL	21.0331 mL
5 mM	0.4207 mL	2.1033 mL	4.2066 mL
10 mM	0.2103 mL	1.0517 mL	2.1033 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Molarity Calculator
Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)

Volume _(start)

Concentration _(final)

Volume _(final)

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

Purity & Documentation

Purity: 98.65%

Select Batch:

Data Sheet (249 KB) SDS (251 KB)

COA (257 KB) HNMR (350 KB) RP-HPLC (240 KB) MS (71 KB)

Handling Instructions (2659 KB)

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	2.1033 mL	10.5166 mL	21.0331 mL	52.5829 mL
	5 mM	0.4207 mL	2.1033 mL	4.2066 mL	10.5166 mL
	10 mM	0.2103 mL	1.0517 mL	2.1033 mL	5.2583 mL
	15 mM	0.1402 mL	0.7011 mL	1.4022 mL	3.5055 mL
	20 mM	0.1052 mL	0.5258 mL	1.0517 mL	2.6291 mL
	25 mM	0.0841 mL	0.4207 mL	0.8413 mL	2.1033 mL
	30 mM	0.0701 mL	0.3506 mL	0.7011 mL	1.7528 mL
	40 mM	0.0526 mL	0.2629 mL	0.5258 mL	1.3146 mL
	50 mM	0.0421 mL	0.2103 mL	0.4207 mL	1.0517 mL