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Cat. No.: HY-170371

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E3 ligase Ligand 47

E3 ligase Ligand 47 is an E3 ligase ligand that can be used to synthesize PROTAC LDD39 (HY-159967).

For research use only. We do not sell to patients.

Formula: C₂₃H₂₇N₃O₅
Molecular Weight:425.48

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (265 KB)

E3 ligase Ligand 47 Chemical Structure

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity

Description

E3 ligase Ligand 47 is an E3 ligase ligand that can be used to synthesize PROTAC LDD39 (HY-159967)^[1].

All Ligands for E3 Ligase Isoforms :

Chemical Information

Molecular Weight 425.48
Formula C₂₃H₂₇N₃O₅
SMILES

O=C(C(CC1)N(C2=O)CC(C=C3)=C2C=C3C(CC4)CCN4[C@@H](C5)C[C@@H]5C(O)=O)NC1=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (265 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Qiao JX, et al. Discovery and Synthesis of Heterobifunctional Degraders of Rearranged during Transfection (RET) Kinase. J Med Chem. 2024 Nov 14;67(21):19736-19754. [Content Brief]

Calculators

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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Biological Activity
- Description
Chemical Information
Purity & Documentation
References

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E3 ligase Ligand 47

All Ligands for E3 Ligase Isoforms

Biological Activity

Chemical Information

Purity & Documentation

References

Calculators

Help & FAQs

E3 ligase Ligand 47 Related Classifications

HY-170371 Related Classifications