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Cat. No.: HY-170371

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E3 ligase Ligand 47

E3 ligase Ligand 47 is an E3 ligase ligand that can be used to synthesize PROTAC LDD39 (HY-159967).

연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.

화학식: C₂₃H₂₇N₃O₅
분자량:425.48

보관:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (265 KB)

E3 ligase Ligand 47 Chemical Structure

사이즈

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity

제품 설명

E3 ligase Ligand 47 is an E3 ligase ligand that can be used to synthesize PROTAC LDD39 (HY-159967)^[1].

All Ligands for E3 Ligase Isoforms :

Chemical Information

분자량 425.48
화학식 C₂₃H₂₇N₃O₅
SMILES

O=C(C(CC1)N(C2=O)CC(C=C3)=C2C=C3C(CC4)CCN4[C@@H](C5)C[C@@H]5C(O)=O)NC1=O
선적

Room temperature in continental US; may vary elsewhere.
보관

Please store the product under the recommended conditions in the Certificate of Analysis.

순도&문서

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (265 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Qiao JX, et al. Discovery and Synthesis of Heterobifunctional Degraders of Rearranged during Transfection (RET) Kinase. J Med Chem. 2024 Nov 14;67(21):19736-19754. [Content Brief]

Calculators

몰농도 계산기

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

농도 희석 계산기

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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MOQ

Minimum order quantity

100 mg

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Biological Activity
- 제품 설명
Chemical Information
순도&문서
References

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E3 ligase Ligand 47

All Ligands for E3 Ligase Isoforms

Biological Activity

Chemical Information

순도&문서

References

Calculators

Help & FAQs

E3 ligase Ligand 47 Related Classifications

HY-170371 Related Classifications