E3 ligase Ligand 56
Based on 1 Customer Validation
E3 ligase Ligand 56 is the ligand for E3 ligase Cereblon and can be used for syntheisis of PROTAC CDK9 degrader-11 (HY-170978).
For research use only. We do not sell to patients.
- Purity: 99.88%
- CAS No.: 1472731-41-1
- Formula: C11H13N3O2
- Molecular Weight:219.24
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Storage:
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
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Cereblon |
Chemical Information
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CAS No. 1472731-41-1
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Appearance Solid
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Molecular Weight 219.24
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Formula C11H13N3O2
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Color Off-white to light blue
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SMILES
O=C(C(NC1=CC=CC(N)=C1)CC2)NC2=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
Solvent & Solubility
DMSO : 50 mg/mL (228.06 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (270 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 4.5612 mL | 22.8061 mL | 45.6121 mL | 114.0303 mL |
| 5 mM | 0.9122 mL | 4.5612 mL | 9.1224 mL | 22.8061 mL | |
| 10 mM | 0.4561 mL | 2.2806 mL | 4.5612 mL | 11.4030 mL | |
| 15 mM | 0.3041 mL | 1.5204 mL | 3.0408 mL | 7.6020 mL | |
| 20 mM | 0.2281 mL | 1.1403 mL | 2.2806 mL | 5.7015 mL | |
| 25 mM | 0.1824 mL | 0.9122 mL | 1.8245 mL | 4.5612 mL | |
| 30 mM | 0.1520 mL | 0.7602 mL | 1.5204 mL | 3.8010 mL | |
| 40 mM | 0.1140 mL | 0.5702 mL | 1.1403 mL | 2.8508 mL | |
| 50 mM | 0.0912 mL | 0.4561 mL | 0.9122 mL | 2.2806 mL | |
| 60 mM | 0.0760 mL | 0.3801 mL | 0.7602 mL | 1.9005 mL | |
| 80 mM | 0.0570 mL | 0.2851 mL | 0.5702 mL | 1.4254 mL | |
| 100 mM | 0.0456 mL | 0.2281 mL | 0.4561 mL | 1.1403 mL |
E3 ligase Ligand 56 Related Classifications
HY-W247437 Related Classifications
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