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Cat. No.: HY-175905

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E3 ligase Ligand 69

E3 ligase Ligand 69 is an E3 ligand that can be used for the synthesis of PROTACs, such as SJH1-51B (HY-162240).

For research use only. We do not sell to patients.

Formula: C₁₉H₂₅NO₄
Molecular Weight:331.41

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

E3 ligase Ligand 69 Chemical Structure

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Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- IC₅₀ & Target
Chemical Information
Purity & Documentation
References
Calculators
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Biological Activity

Description

E3 ligase Ligand 69 is an E3 ligand that can be used for the synthesis of PROTACs, such as SJH1-51B (HY-162240)^[1].

IC₅₀ & Target^[1]

SKP1

All Ligands for E3 Ligase Isoforms :

Chemical Information

Molecular Weight 331.41
Formula C₁₉H₂₅NO₄
SMILES

O=C(O)CCCOC1=CC=CC(CC2CCN(C(C=C)=O)CC2)=C1
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Handling Instructions (2659 KB)

References

[1]. Hong SH, et al. Exploiting the Cullin E3 Ligase Adaptor Protein SKP1 for Targeted Protein Degradation. ACS Chem Biol. 2024 Feb 16;19(2):442-450. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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Biological Activity
- Description
- IC₅₀ & Target
Chemical Information
Purity & Documentation
References

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E3 ligase Ligand 69

All Ligands for E3 Ligase Isoforms

Biological Activity

Chemical Information

Purity & Documentation

References

Calculators

Help & FAQs

E3 ligase Ligand 69 Related Classifications

HY-175905 Related Classifications