CGS-9896
Based on 1 Customer Validation
CGS-9896 is an orally active benzodiazepine receptor agonist that targets the benzodiazepine receptor allosterically coupled to the GABAA receptor and chloride ion carrier channel. The Ki value of CGS-9896 for benzodiazepine receptors in rats is 0.83 nM. CGS-9896 inhibits pentylenetetrazol-induced convulsions in mice and exerts an anticonvulsant effect.
Para uso exclusivo en investigación. No vendemos a pacientes.
- No. CAS: 77779-36-3
- Fòrmula: C16H10ClN3O
- Peso molecular:295.73
-
Almacenamiento:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
Actividad biológica
-
Chemical Information
- Pureza y Documentación
- Referencias
-
Help & FAQs
Actividad biológica
Descripciòn
In Vivo
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
-
Animal Model:Male mice[1]
-
Dosage:1.17 mg/kg
-
Administration:p.o.
-
Result:Exhibited agonist (anticonvulsant) activity with an ED50 of 1.17 mg/kg, representing the dose required to prevent tonic convulsions and death in 50% of treated mice.
Chemical Information
-
No. CAS 77779-36-3
-
Appearance Solid
-
Peso molecular 295.73
-
Fòrmula C16H10ClN3O
-
Color Light yellow to yellow
-
SMILES
O=C1C2=CNC=3C=CC=CC3C2=NN1C4=CC=C(Cl)C=C4
-
Envío
Room temperature in continental US; may vary elsewhere.
-
Almacenamiento
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Pureza y Documentación
Referencias
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
CGS-9896 Related Classifications
HY-103052 Related Classifications
Powered by Bioz