77779-36-3
Chemical Structure
CGS-9896
- CAS No.: 77779-36-3
- Formula:C16H10ClN3O
- Molecular Weight:295.73
IUPAC Name: 2-(4-chlorophenyl)-2,5-dihydro-3H-pyrazolo[4,3-c]quinolin-3-one
InChIKey: CQINXWYVIOMBEI-UHFFFAOYSA-N
SMILES: O=C1C2=CNC=3C=CC=CC3C2=NN1C4=CC=C(Cl)C=C4
Biological Activity: CGS-9896 is an orally active benzodiazepine receptor agonist that targets the benzodiazepine receptor allosterically coupled to the GABAA receptor and chloride ion carrier channel. The Ki value of CGS-9896 for benzodiazepine receptors in rats is 0.83 nM. CGS-9896 inhibits pentylenetetrazol-induced convulsions in mice and exerts an anticonvulsant effect[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
|
CGS-9896 | CGS-9896 is an orally active benzodiazepine receptor agonist that targets the benzodiazepine receptor allosterically coupled to the GABAA receptor and chloride ion carrier channel. The Ki value of CGS-9896 for benzodiazepine receptors in rats is 0.83 nM. CGS-9896 inhibits pentylenetetrazol-induced convulsions in mice and exerts an anticonvulsant effect. | |||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
Keywords
