Ethyl 5-hydroxy-2-methyl-1H-indole-3-carboxylate

製品番号: HY-W009757 純度: 99.64%: Data Sheet SDS COA 取扱説明書
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Ethyl 5-hydroxy-2-methyl-1H-indole-3-carboxylate is an active compound, and can be used in the synthesis of 2-phenylthiomethyl-indole derivatives, 2-phenylthiomethyl-indole derivative is a 5-lipoxygenase (5-LO) inhibitor.

商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。

Ethyl 5-hydroxy-2-methyl-1H-indole-3-carboxylate 構造式

CAS 番号 : 7598-91-6

容量	価格（税別）	在庫状況	数量
Solid + Solvent (Highly Recommended)
10 mM * 1 mL in DMSO ready for reconstitution	USD 35	在庫あり	Estimated Time of Arrival: December 31
Solution
10 mM * 1 mL in DMSO	USD 35	在庫あり	Estimated Time of Arrival: December 31
Solid
100 mg	$32	在庫あり	Estimated Time of Arrival: December 31
500 mg	$61	在庫あり	Estimated Time of Arrival: December 31
1 g	$80	在庫あり	Estimated Time of Arrival: December 31
5 g		お問い合わせ
10 g		お問い合わせ

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* アイテムを追加する前、数量をご選択ください

This product is a controlled substance and not for sale in your territory.

Lipoxygenase アイソフォーム固有の製品をすべて表示:

すべてのアイソフォームを表示

5-LOX 12-LOX 15-LOX

生物活性
純度とドキュメンテーション
参考文献
カスタマーレビュー

製品説明

分子量

219.24

分子式

C₁₂H₁₃NO₃

CAS 番号

7598-91-6

Appearance

Solid

Color

Off-white to light brown

SMILES

CCOC(C(C1=C2C=CC(O)=C1)=C(N2)C)=O

輸送条件

Room temperature in continental US; may vary elsewhere.

保管条件

Powder	-20°C	3 years
	4°C	2 years
In solvent	-80°C	6 months
	-20°C	1 month

溶剤 & 溶解度

体外:

DMSO : 100 mg/mL (456.12 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	4.5612 mL	22.8061 mL	45.6121 mL
5 mM	0.9122 mL	4.5612 mL	9.1224 mL
10 mM	0.4561 mL	2.2806 mL	4.5612 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Molarity Calculator
Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

一般には略語で表示されます：C₁V₁ = C₂V₂

濃度 _（開始）

体積 _（開始）

濃度 _（終了）

体積 _（終了）

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

純度とドキュメンテーション

純度: 99.64%

Select Batch:

データシート (270 KB) SDS (393 KB)

COA (251 KB) HNMR (124 KB) RP-HPLC (283 KB)

取扱説明書 (2659 KB)

参考文献

[1]. Peduto A, et al. Further studies on ethyl 5-hydroxy-indole-3-carboxylate scaffold: design, synthesis and evaluation of 2-phenylthiomethyl-indole derivatives as efficient inhibitors of human 5-lipoxygenase. Eur J Med Chem. 2014 Jun 23;81:492-8. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	4.5612 mL	22.8061 mL	45.6121 mL	114.0303 mL
	5 mM	0.9122 mL	4.5612 mL	9.1224 mL	22.8061 mL
	10 mM	0.4561 mL	2.2806 mL	4.5612 mL	11.4030 mL
	15 mM	0.3041 mL	1.5204 mL	3.0408 mL	7.6020 mL
	20 mM	0.2281 mL	1.1403 mL	2.2806 mL	5.7015 mL
	25 mM	0.1824 mL	0.9122 mL	1.8245 mL	4.5612 mL
	30 mM	0.1520 mL	0.7602 mL	1.5204 mL	3.8010 mL
	40 mM	0.1140 mL	0.5702 mL	1.1403 mL	2.8508 mL
	50 mM	0.0912 mL	0.4561 mL	0.9122 mL	2.2806 mL
	60 mM	0.0760 mL	0.3801 mL	0.7602 mL	1.9005 mL
	80 mM	0.0570 mL	0.2851 mL	0.5702 mL	1.4254 mL
	100 mM	0.0456 mL	0.2281 mL	0.4561 mL	1.1403 mL