1. NF-κB
    Immunology/Inflammation
  2. NF-κB
    NO Synthase
    COX
    PGE synthase
  3. Ethyl Caffeate

Ethyl Caffeate 

Cat. No.: HY-N6966
Handling Instructions

Ethyl Caffeate is a natural phenolic compound isolated from Bidens pilosa. Ethyl caffeate suppresses NF-κB activation and its downstream inflammatory mediators, inducible nitric oxide synthase (iNOS), cyclooxygenase-2 (COX-2), and prostaglandin E2 (PGE2) in vitro or in mouse skin.

For research use only. We do not sell to patients.

Ethyl Caffeate Chemical Structure

Ethyl Caffeate Chemical Structure

CAS No. : 102-37-4

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Description

Ethyl Caffeate is a natural phenolic compound isolated from Bidens pilosa. Ethyl caffeate suppresses NF-κB activation and its downstream inflammatory mediators, inducible nitric oxide synthase (iNOS), cyclooxygenase-2 (COX-2), and prostaglandin E2 (PGE2) in vitro or in mouse skin[1].

IC50 & Target

NF-κB

 

COX-2

 

In Vitro

Ethyl Caffeate markedly suppresses the lipopolysaccharide (LPS)-induced nitric oxide (NO) production with IC50 of 5.5 μg/ml[1].

Molecular Weight

208.21

Formula

C₁₁H₁₂O₄

CAS No.

102-37-4

SMILES

O=C(OCC)/C=C/C1=CC=C(O)C(O)=C1

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Room temperature in continental US; may vary elsewhere

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

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Ethyl Caffeate
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HY-N6966
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