1. Metabolic Enzyme/Protease Neuronal Signaling
  2. FAAH
  3. FAAH/MAGL-IN-4

FAAH/MAGL-IN-4 (Compound 13) is a potent fatty acid amide hydrolase (FAAH) and monoglyceride lipase (MGL) inhibitor with IC50s of 9.1 nM and 7.9 μM, respectively. FAAH/MAGL-IN-4 can be used for the research of pain and CNS disorders.

For research use only. We do not sell to patients.

FAAH/MAGL-IN-4 Chemical Structure

FAAH/MAGL-IN-4 Chemical Structure

CAS No. : 256383-45-6

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Based on 1 publication(s) in Google Scholar

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Description

FAAH/MAGL-IN-4 (Compound 13) is a potent fatty acid amide hydrolase (FAAH) and monoglyceride lipase (MGL) inhibitor with IC50s of 9.1 nM and 7.9 μM, respectively. FAAH/MAGL-IN-4 can be used for the research of pain and CNS disorders[1].

IC50 & Target

IC50: 9.1 nM (FAAH), 7.9 μM (MAGL)[1]

Molecular Weight

248.17

Formula

C15H25BO2

CAS No.
Appearance

Solid

Color

White to off-white

SMILES

CCCCCCCCCC1=CC=C(C=C1)B(O)O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 125 mg/mL (503.69 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 4.0295 mL 20.1475 mL 40.2950 mL
5 mM 0.8059 mL 4.0295 mL 8.0590 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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This equation is commonly abbreviated as: C1V1 = C2V2

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In Vivo Dissolution Calculator
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Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 4.0295 mL 20.1475 mL 40.2950 mL 100.7374 mL
5 mM 0.8059 mL 4.0295 mL 8.0590 mL 20.1475 mL
10 mM 0.4029 mL 2.0147 mL 4.0295 mL 10.0737 mL
15 mM 0.2686 mL 1.3432 mL 2.6863 mL 6.7158 mL
20 mM 0.2015 mL 1.0074 mL 2.0147 mL 5.0369 mL
25 mM 0.1612 mL 0.8059 mL 1.6118 mL 4.0295 mL
30 mM 0.1343 mL 0.6716 mL 1.3432 mL 3.3579 mL
40 mM 0.1007 mL 0.5037 mL 1.0074 mL 2.5184 mL
50 mM 0.0806 mL 0.4029 mL 0.8059 mL 2.0147 mL
60 mM 0.0672 mL 0.3358 mL 0.6716 mL 1.6790 mL
80 mM 0.0504 mL 0.2518 mL 0.5037 mL 1.2592 mL
100 mM 0.0403 mL 0.2015 mL 0.4029 mL 1.0074 mL
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FAAH/MAGL-IN-4 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
FAAH/MAGL-IN-4
Cat. No.:
HY-118158
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