PF-622
Based on 1 publication(s) in Google Scholar
PF-622 is a selective FAAH inhibitor, and can be used for study of analgesic and anxiolytic/antidepressant.
For research use only. We do not sell to patients.
- CAS No.: 898235-65-9
- Formula: C21H22N4O
- Molecular Weight:346.43
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Storage:Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
Publications Citing Use of MedChemExpress (MCE) PF-622
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Biological Activity
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| HEK293 | EC50 |
>25 μM
Compound: PF-622
|
Antagonist activity at human TRPA1 expressed in HEK293 cells assessed as decrease in intracellular calcium level
Antagonist activity at human TRPA1 expressed in HEK293 cells assessed as decrease in intracellular calcium level
|
[PMID: 19875281] |
| HEK293 | IC50 |
>10 μM
Compound: PF-622
|
Antagonist activity at human TRPV1 expressed in HEK293 cells assessed as decrease in intracellular calcium level
Antagonist activity at human TRPV1 expressed in HEK293 cells assessed as decrease in intracellular calcium level
|
[PMID: 19875281] |
Chemical Information
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CAS No. 898235-65-9
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Appearance Solid
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Molecular Weight 346.43
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Formula C21H22N4O
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SMILES
O=C(N1CCN(CC1)CC2=NC3=C(C=C2)C=CC=C3)NC4=CC=CC=C4
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years In solvent -80°C 6 months -20°C 1 month
Publications (1)
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Journal Impact Factor
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Most Recent
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Chin Med
Electroacupuncture to point Baihui confers anxiolytic effects by promoting oxytocin release from PVN in Mice. [Abstract]2026 Jan 13;21(1):30. PMID: 41530867
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)