2. Metabolic Enzyme/Protease Neuronal Signaling
  3. FAAH
  4. PF-622

PF-622 is a selective FAAH inhibitor, and can be used for study of analgesic and anxiolytic/antidepressant.

For research use only. We do not sell to patients.

PF-622

PF-622 Chemical Structure

CAS No. : 898235-65-9

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Based on 1 publication(s) in Google Scholar

PF-622 Related Antibodies

Top Publications Citing Use of Products

1 Publications Citing Use of MCE PF-622

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Description

PF-622 is a selective FAAH inhibitor, and can be used for study of analgesic and anxiolytic/antidepressant[1].

Cellular Effect
Cell Line Type Value Description References
HEK293 EC50
> 25 μM
Compound: PF-622
Antagonist activity at human TRPA1 expressed in HEK293 cells assessed as decrease in intracellular calcium level
Antagonist activity at human TRPA1 expressed in HEK293 cells assessed as decrease in intracellular calcium level
[PMID: 19875281]
HEK293 IC50
> 10 μM
Compound: PF-622
Antagonist activity at human TRPV1 expressed in HEK293 cells assessed as decrease in intracellular calcium level
Antagonist activity at human TRPV1 expressed in HEK293 cells assessed as decrease in intracellular calcium level
[PMID: 19875281]
Molecular Weight

346.43

Formula

C21H22N4O
CAS No.
SMILES

O=C(N1CCN(CC1)CC2=NC3=C(C=C2)C=CC=C3)NC4=CC=CC=C4
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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PF-622 Related Classifications

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

PF-622898235-65-9PF622PF 622FAAHFatty acid amide hydrolaseanalgesicanxiolytic/antidepressantInhibitorinhibitorinhibit

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HY-10867
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