ML395
Based on 1 publication(s) in Google Scholar
ML395 is a potent and selective allosteric inhibitor of phospholipase D2 with antiviral activity. The cellular PLD1 IC50 value of ML395 exceeds 30,000 nM, while its cellular PLD2 IC50 value is 360 nM. ML395 shows excellent pharmacokinetic characteristics in vitro and physiochemical properties superior to other reported phospholipase inhibitors. ML395 shows interesting antiviral activity in cell-based assays against multiple influenza virus strains (H1, H3, H5, and H7).
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- No. CAS: 1638957-17-1
- Fòrmula: C26H29N5O2
- Peso molecular:443.54
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Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Publications Citing Use of MedChemExpress (MCE) ML395
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Actividad biológica
Chemical Information
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No. CAS 1638957-17-1
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Peso molecular 443.54
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Fòrmula C26H29N5O2
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SMILES
O=C(C1=CC=C2C=CC=CC2=C1)NCCN(CC3)CCC3(N(CC4=CC=CN=C4)CN5)C5=O
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Publications (1)
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Journal Impact Factor
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Most Recent
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Am J Orthod Dentofacial Orthop
Force threshold-dependent modulation of root resorption via the Nrf2/Keap1/p62 antioxidant pathway during orthodontic tooth movement. [Abstract]2025 Dec 4:S0889-5406(25)00481-0. PMID: 41342829
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Referencias
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
ML395 Related Classifications
HY-124305 Related Classifications
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