N3-PEG3-C2-PFP ester
N3-PEG3-C2-PFP ester is a nonclaevable 3-unit PEG linker used in the synthesis of antibody-drug conjugates (ADCs). N3-PEG3-C2-PFP ester is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
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- No. CAS: 1807530-07-9
- Fòrmula: C15H16F5N3O5
- Peso molecular:413.30
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Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Actividad biológica
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Chemical Information
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Solvente y solubilidad
- Pureza y Documentación
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Help & FAQs
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Actividad biológica
Descripciòn
IC50 & Target
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Non-cleavable Linker |
Chemical Information
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No. CAS 1807530-07-9
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Peso molecular 413.30
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Fòrmula C15H16F5N3O5
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SMILES
O=C(OC1=C(F)C(F)=C(F)C(F)=C1F)CCOCCOCCOCCN=[N+]=[N-]
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Solvente y solubilidad
In Vitro:
DMSO : 100 mg/mL (241.95 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Pureza y Documentación
Complete Stock Solution Preparation Table
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.4196 mL | 12.0978 mL | 24.1955 mL | 60.4888 mL |
| 5 mM | 0.4839 mL | 2.4196 mL | 4.8391 mL | 12.0978 mL | |
| 10 mM | 0.2420 mL | 1.2098 mL | 2.4196 mL | 6.0489 mL | |
| 15 mM | 0.1613 mL | 0.8065 mL | 1.6130 mL | 4.0326 mL | |
| 20 mM | 0.1210 mL | 0.6049 mL | 1.2098 mL | 3.0244 mL | |
| 25 mM | 0.0968 mL | 0.4839 mL | 0.9678 mL | 2.4196 mL | |
| 30 mM | 0.0807 mL | 0.4033 mL | 0.8065 mL | 2.0163 mL | |
| 40 mM | 0.0605 mL | 0.3024 mL | 0.6049 mL | 1.5122 mL | |
| 50 mM | 0.0484 mL | 0.2420 mL | 0.4839 mL | 1.2098 mL | |
| 60 mM | 0.0403 mL | 0.2016 mL | 0.4033 mL | 1.0081 mL | |
| 80 mM | 0.0302 mL | 0.1512 mL | 0.3024 mL | 0.7561 mL | |
| 100 mM | 0.0242 mL | 0.1210 mL | 0.2420 mL | 0.6049 mL |
N3-PEG3-C2-PFP ester Related Classifications
HY-126529 Related Classifications
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