Referencia número: HY-N3961

Neoglycyrol

1 Cited Publications

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Based on 1 publication(s) in Google Scholar

Neoglycyrol is isolated from the root of Glycyrrhiza uralensis Fisch. Neoglycyrol is a potential myocardial protection active compound screened from traditional patent medicine Tongmai Yangxin pill (TMYXP).

Para uso exclusivo en investigación. No vendemos a pacientes.

Pureza: 99.23%
No. CAS: 23013-84-5
Fòrmula: C₂₁H₁₈O₆
Peso molecular:366.36

Almacenamiento:

4°C, protect from light

* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

Neoglycyrol Chemical Structure

No. CAS: 23013-84-5

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Actividad biológica
- Descripciòn
Chemical Information
Publications (1)
Solvente y solubilidad
- In Vitro
- In Vivo
Pureza y Documentación
Referencias
Help & FAQs
Classifications
Bioz

Actividad biológica

Descripciòn

Neoglycyrol is isolated from the root of Glycyrrhiza uralensis Fisch^[1]. Neoglycyrol is a potential myocardial protection active compound screened from traditional patent medicine Tongmai Yangxin pill (TMYXP)^[2].

Chemical Information

No. CAS 23013-84-5
Appearance Solid
Peso molecular 366.36
Fòrmula C₂₁H₁₈O₆
Color White to off-white
SMILES

O=C1C2=C(OC3=CC(O)=CC=C32)C4=C(OC)C(C/C=C(C)\C)=C(O)C=C4O1
Structure Classification
- Phenols
- Polyphenols
Initial Source
Envío

Room temperature in continental US; may vary elsewhere.
Almacenamiento

4°C, protect from light

* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

Publications (1)

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Bioorg Chem

Interpretable machine learning and molecular simulations identify natural pancreatic lipase inhibitors and hydrophobic hotspot residues. [Abstract]

2026 Jul 15:176:109873. PMID: 41997005

Solvente y solubilidad

In Vitro:

DMSO : 16.67 mg/mL (45.50 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

View the Complete Stock Solution Preparation Table

Preparing Stock Solutions

View the Complete Stock Solution Preparation Table

Concentration Solvent Mass

1 mg

5 mg

10 mg

Concentration

Solvent

Mass

1 mM

2.7296 mL

13.6478 mL

27.2956 mL

5 mM

0.5459 mL

2.7296 mL

5.4591 mL

10 mM

0.2730 mL

1.3648 mL

2.7296 mL

Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.

Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Calculadora de molaridad

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

Calculadora de dilución

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

In Vivo:

Select the appropriate dissolution method based on your experimental animal and administration route.

Stock Solution Working Solution

For the following dissolution methods, please ensure to first prepare a clear stock solution using an In Vitro approach and then sequentially add co-solvents:
To ensure reliable experimental results, the clarified stock solution can be appropriately stored based on storage conditions. As for the working solution for In Vivo experiments, it is recommended to prepare freshly and use it on the same day.
The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.

Protocol 1

Add each solvent one by one: 10% DMSO 90% Corn Oil

Solubility: ≥ 1.67 mg/mL (4.56 mM); Clear solution

This protocol yields a clear solution of ≥ 1.67 mg/mL (saturation unknown). If the continuous dosing period exceeds half a month, please choose this protocol carefully.

Taking 1 mL working solution as an example, add 100 μL DMSO stock solution (16.7 mg/mL) to 900 μL Corn oil, and mix evenly.

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage Dosage
mg/kg
Animal Weight (Per Animal) Animal Weight (Per Animal)
g
Dosing Volume (Per Animal) Dosing Volume (Per Animal)
μL
Number of Animals Number of Animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Please enter your animal formula composition:

%
DMSO +

Recommended: Keep the proportion of DMSO in working solution below 2% if your animal is weak.
%
+
+
%
Tween-80 + +
%
Saline +

The co-solvents required include: DMSO, . All of co-solvents are available by MedChemExpress (MCE). , Tween 80. All of co-solvents are available by MedChemExpress (MCE).

Working solution concentration: 0.22 mg/mL

Pureza y Documentación

Select Batch:

Pureza: 99.98%

Assay: 99.98%

ee.: 99.98%

Ficha de datos (275 KB)
SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instrucciones de manejo (2659 KB)

Referencias

[1]. Wang CL, et al. Chemical studies of coumarins from Glycyrrhiza uralensis Fisch. Yao Xue Xue Bao. 1991;26(2):147-51. [Content Brief]

[2]. Tao S, et al. Screening of active compounds with myocardial protective effects from Tongmai Yangxin pill. Zhejiang Da Xue Xue Bao Yi Xue Ban. 2015 Mar;44(2):145-53. [Content Brief]

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg
DMSO	1 mM	2.7296 mL	13.6478 mL	27.2956 mL	68.2389 mL
	5 mM	0.5459 mL	2.7296 mL	5.4591 mL	13.6478 mL
	10 mM	0.2730 mL	1.3648 mL	2.7296 mL	6.8239 mL
	15 mM	0.1820 mL	0.9099 mL	1.8197 mL	4.5493 mL
	20 mM	0.1365 mL	0.6824 mL	1.3648 mL	3.4119 mL
	25 mM	0.1092 mL	0.5459 mL	1.0918 mL	2.7296 mL
	30 mM	0.0910 mL	0.4549 mL	0.9099 mL	2.2746 mL
	40 mM	0.0682 mL	0.3412 mL	0.6824 mL	1.7060 mL

Keywords

Neoglycyrol

1 Cited Publications

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Neoglycyrol

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Publications Citing Use of MedChemExpress (MCE) Neoglycyrol

Actividad biológica

Chemical Information

Publications (1)

Solvente y solubilidad

Pureza y Documentación

Referencias

Help & FAQs

Complete Stock Solution Preparation Table