Norbornene-NHS
Based on 1 Customer Validation
Norbornene-NHS is a norbornene-functionalized antibody-drug conjugate linker (ADC Linker) bearing an NHS ester, which is applicable for highly efficient and specific antibody conjugation reactions in ADC research and development. Norbornene-NHS also acts as an azide-group-containing click chemistry reagent, serving as a dienophile for copper-free click reaction conjugation.
Para uso exclusivo en investigación. No vendemos a pacientes.
- Pureza : 92.08%
- No. CAS: 1888335-48-5
- Fòrmula: C12H13NO5
- Peso molecular:251.24
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Almacenamiento:
-20°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
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Actividad biológica
Descripciòn
In Vitro
Norbornene-NHS (1 h) efficiently couples to Fmoc-deprotected proteasome inhibitor scaffold 6 in DMF with DIPEA to produce norbornene-functionalized proteasome inhibitor Nor-Ahx3L3VS 8 in 94% yield[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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No. CAS 1888335-48-5
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Appearance Liquid (Density: 1.42±0.1 g/cm3)
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Peso molecular 251.24
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Fòrmula C12H13NO5
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Color Light yellow to yellow
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SMILES
O=C(OC1CC2C=CC1C2)ON3C(CCC3=O)=O
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
-20°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Pureza y Documentación
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Ficha de datos (271 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Instrucciones de manejo (2659 KB)
Referencias
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)