ITCH - itchy E3 ubiquitin protein ligase Gene

Felis catus

Gene ID: 101086133 | Gene type: protein coding

About ITCH

mRNA	Protein	Name
XM_003983597.6	XP_003983646.1	E3 ubiquitin-protein ligase Itchy homolog isoform X1
XM_011280854.4	XP_011279156.1	E3 ubiquitin-protein ligase Itchy homolog isoform X1
XM_006929828.5	XP_006929890.1	E3 ubiquitin-protein ligase Itchy homolog isoform X1
XM_019826622.2	XP_019682181.1	E3 ubiquitin-protein ligase Itchy homolog isoform X2

Protein Preferred Names

Protein Names

E3 ubiquitin-protein ligase Itchy homolog

Approval

Bioactive Molecules (5)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-B0548A	Hydroxyzine dihydrochloride	Antagonist	99.59%	Unkown
HY-B1183	Hydrocortisone acetate	Agonist	99.07%	Yes
HY-B0548	Hydroxyzine	Antagonist	99.72%	Unkown
HY-B1173	(+)-Camphor	Inhibitor	98.94%	Unkown
HY-106566	Alclometasone dipropionate		≥96.0%	Unkown

Inhibitory Antibodies (2)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-P99025	Lebrikizumab	Inhibitor	99.90%	Unkown
HY-P99162	Nemolizumab	Inhibitor	99.70%	Unkown

Clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Phase
HY-14939	Vapitadine		99.77%	Phase 2

Pre-clinical Phase

Bioactive Molecules (35)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-129047	Trypsin	Activator	91.00%	Unkown
HY-129047A	Trypsin (MS grade)	Activator	95.00%	Unkown
HY-103368	Eact	Activator	98.86%	Unkown
HY-118069	(R)-ZINC-3573	Agonist	99.83%	Unkown
HY-148949	Kallikrein 5-IN-2		99.46%	Unkown
HY-147051	Nelremagpran		99.94%	Unkown
HY-148244	MS47134		99.69%	Unkown
HY-103320A	Calhex 231 hydrochloride	Inhibitor	99.81%	Unkown
HY-165559	Trpvicin	Inhibitor	99.4%	Unkown
HY-145997	MRGPRX4 modulator-1		98.96%	Unkown
HY-B1144A	Chlormidazole hydrochloride	Inhibitor	99.45%	Unkown
HY-103320B	(1R,2R)-Calhex 231 hydrochloride	Control	98.45%	Unkown
HY-143481	Nav1.8-IN-2	Inhibitor	99.83%	Unkown
HY-171366	lirucitinib	Inhibitor	98.72%	Unkown
HY-108425B	(Rac)-AMG8379	Antagonist	99.25%	Unkown
HY-145153	S-777469	Agonist	98.19%	Unkown
HY-153275A	KM-001-E2		99.08%	Unkown
HY-108425	AMG8379	Antagonist	/	Unkown
HY-103320	Calhex 231	Antagonist	/	Unkown
HY-108425A	AMG8380	Inhibitor	/	Unkown
HY-124356	Alcaftadine carboxylic acid		/	Unkown
HY-124356AS	Alcaftadine carboxylic acid-d3 sodium		/	Unkown
HY-135495	AM-0466	Inhibitor	/	Unkown
HY-157496	EP3 antagonist 7	Antagonist	/	Unkown
HY-163840	GFRα2/3-IN-1	Inhibitor	/	Unkown
HY-175672	MRGPRX4 modulator-3	Modulator	/	Unkown
HY-182517	AG1529	Antagonist	/	Unkown
HY-182710	DA-0218	Inhibitor	/	Unkown
HY-P5357	SFNGGP-NH2		/	Unkown
HY-RS06943	ITCH Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown
HY-W665882	Norketotifen	Inhibitor	/	Unkown
HY-167645	Pramoxine		/	Unkown
HY-N12040	γ-Isofagarine		/	Unkown
HY-RS17888	Itch Mouse Pre-designed siRNA Set A	Pre-designed Set	/	Unkown
HY-RS24357	Itch Rat Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Species	Symbol	Source	ID
Homo sapiens	ITCH	NCBI	NCBI:83737
Mus musculus	ITCH	NCBI	NCBI:16396

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