2. Immunology/Inflammation
  3. Kallikrein
  4. Kallikrein 5-IN-2

Kallikrein 5-IN-2 (compound 21) is a selective Kallikrein KLK5 inhibitor (pIC50=7.1). KLK5 inhibition may normalise epidermal shedding and reduce the associated inflammation and itching.

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Kallikrein 5-IN-2 Chemical Structure

Kallikrein 5-IN-2 Chemical Structure

CAS No. : 2361160-57-6

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Kallikrein 5-IN-2 Related Antibodies

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Description

Kallikrein 5-IN-2 (compound 21) is a selective Kallikrein KLK5 inhibitor (pIC50=7.1). KLK5 inhibition may normalise epidermal shedding and reduce the associated inflammation and itching[1].

IC50 & Target

Kallikrein 5[1]
Molecular Weight

398.46

Formula

C23H22N6O
CAS No.
SMILES

N=C(C1=CC=C(NCC2=NC=C(C3=CC=CC=C3)N2)C=C1OCC4=CC=CN=C4)N
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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Kallikrein 5-IN-2 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Kallikrein 5-IN-22361160-57-6KallikreinKLKKallikrein-related peptidaseInhibitorinhibitorinhibit

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