Serpina1d - serine (or cysteine) peptidase inhibitor, clade A, member 1D Gene

Also Known as AAT; PI4; Dom1; Dom4; DOM-7; Spi1-1; Spi1-4; Serpina1a

Species: Mus musculus

Gene Type: protein coding
Gene ID: 20703

Summary

Predicted to enable identical protein binding activity; protease binding activity; and serine-type endopeptidase inhibitor activity. Acts upstream of or within response to cytokine and response to peptide hormone. Located in extracellular region. Is expressed in gut and liver lobe. Human ortholog(s) of this gene implicated in several diseases, including alpha 1-antitrypsin deficiency; artery disease (multiple); chronic obstructive pulmonary disease (multiple); inflammatory bowel disease (multiple); and liver disease (multiple). Orthologous to human SERPINA1 (Serpin family A member 1). [provided by Alliance of Genome Resources, Apr 2022]

Serpina1d Products (2)

mRNA Protein Name
NM_009246.3 NP_033272.1 alpha-1-antitrypsin 1-4 precursor
NM_009246.3 NP_033272.1 alpha-1-antitrypsin 1月4日 precursor

Gene Ontology

  • Biological Process
  • Cellular Component
Biological Process GO Annotation Evidence References Source
acts upstream of or within response to cytokine IDA
IDA: Inferred from direct assay
15795238 MGI
acts upstream of or within response to peptide hormone IDA
IDA: Inferred from direct assay
15795238 MGI
Cellular Component GO Annotation Evidence References Source
located in extracellular region IDA
IDA: Inferred from direct assay
11961105 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

alpha-1-antitrypsin 1-4

  • Alpha-1 protease inhibitor 1

  • Alpha-1-antiproteinase

  • Alpha-1-antitrypsin 1-1

  • Serine protease inhibitor 1-1

  • Serine protease inhibitor A1a

  • Serpin A1a

  • Serpina1 DOM-7

  • alpha-1 protease inhibitor 4

  • serine (or cysteine) proteinase inhibitor, clade A, memb

Recombinant Serpina1d Proteins

Cat. No. Product Name Accession Purity
HY-P77484 Serpina1d Protein, Mouse (HEK293) XP_003945711.1 (E25-K413) ≥ 85%, as determined by reducing SDS-PAGE.
HY-P77485 Serpina1d Protein, Mouse (HEK293, Fc) XP_003945711.1 (E25-K413) ≥ 95%, as determined by reducing SDS-PAGE.
HY-P77486 Serpina1d Protein, Mouse (HEK293, His) XP_003945711.1 (E25-K413) ≥ 95%, as determined by reducing SDS-PAGE.