Gstp1 - glutathione S-transferase pi 1 Gene

Also Known as Gst3; Gstp; GST-P; Gstp2

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 24426

Summary

Enables organic cyclic compound binding activity; protein kinase binding activity; and toxic substance binding activity. Involved in several processes, including cellular response to cell-matrix adhesion; cellular response to epidermal growth factor stimulus; and cellular response to hormone stimulus. Located in cytosol; nucleus; and plasma membrane. Biomarker of cholestasis; pre-malignant neoplasm; prostate carcinoma in situ; prostatic hypertrophy; and urinary bladder Cancer. Human ortholog(s) of this gene implicated in several diseases, including brain disease (multiple); carcinoma (multiple); hematologic Cancer (multiple); reproductive organ Cancer (multiple); and respiratory system disease (multiple). Orthologous to human GSTP1 (Glutathione S-transferase pi 1). [provided by Alliance of Genome Resources, Apr 2022]

Gstp1 Products (1)

mRNA Protein Name
NM_012577.2 NP_036709.1 glutathione S-transferase P

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence References Source
enables organic cyclic compound binding IPI
IPI: Inferred from physical interaction
11018474 RGD
enables protein kinase binding IPI
IPI: Inferred from physical interaction
23741294 RGD
enables toxic substance binding IPI
IPI: Inferred from physical interaction
11018474 RGD
Biological Process GO Annotation Evidence References Source
involved in animal organ regeneration IEP
IEP: Inferred from expression pattern
7499462 RGD
involved in cellular response to cell-matrix adhesion IEP
IEP: Inferred from expression pattern
10793289 RGD
involved in cellular response to epidermal growth factor stimulus IEP
IEP: Inferred from expression pattern
1908848 RGD
involved in cellular response to glucocorticoid stimulus IEP
IEP: Inferred from expression pattern
18349876 RGD
involved in cellular response to insulin stimulus IEP
IEP: Inferred from expression pattern
1908848 RGD
involved in negative regulation of protein kinase activity IMP
IMP: Inferred from mutant phenotype
21668448 RGD
involved in negative regulation of smooth muscle cell chemotaxis IMP
IMP: Inferred from mutant phenotype
24321768 RGD
involved in negative regulation of vascular associated smooth muscle cell proliferation IMP
IMP: Inferred from mutant phenotype
24321768 RGD
involved in oligodendrocyte development IEP
IEP: Inferred from expression pattern
17681700 RGD
involved in response to L-ascorbic acid IEP
IEP: Inferred from expression pattern
9834927 RGD
involved in response to amino acid IEP
IEP: Inferred from expression pattern
20013880 RGD
involved in response to estradiol IEP
IEP: Inferred from expression pattern
9505896 RGD
involved in response to ethanol IEP
IEP: Inferred from expression pattern
2206462 RGD
involved in response to nutrient levels IEP
IEP: Inferred from expression pattern
16317157 RGD
involved in response to toxic substance IEP
IEP: Inferred from expression pattern
19790251 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

glutathione S-transferase P

  • GST 7-7

  • GST class-pi

  • Glutathione-S-transferase, placental enzyme pi type

  • chain 7

  • glutathione S-transferase, pi 2

Recombinant Gstp1 Proteins

Cat. No. Product Name Accession Purity
HY-P72217 GSTP1 Protein, Rat (His) P04906 (P2-Q210) ≥ 90%, as determined by reducing SDS-PAGE.

Related Agents

  • Clinical Phase
  • Pre-clinical Phase

Clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name Effect
Purity Phase
HY-16123 Canfosfamide hydrochloride Chemical / Phase 3
HY-13634 Ezatiostat hydrochloride / Phase 2
HY-13634A Ezatiostat 99.82% Phase 1

Pre-clinical Phase

Bioactive Molecules (19)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-135318 NBDHEX 99.22% Unkown
HY-115673 LAS17 Inhibitor 97.46% Unkown
HY-13634B TLK117 Inhibitor 99.86% Unkown
HY-112534 GSTO-IN-2 Inhibitor 98.0% Unkown
HY-P2961 Glutathione S-transferase / Unkown
HY-145413 BRD2889 Inhibitor / Unkown
HY-132913 Cyclopropenone probe 1 / Unkown
HY-157426 PROTAC BRD4 Degrader-50 Degrader / Unkown
HY-160455 GSTP1-1 inhibitor 1 / Unkown
HY-169058 GSTP1-1 inhibitor 2 Inhibitor / Unkown
HY-178372 GSTO1-IN-4 Inhibitor / Unkown
HY-179217 GSTP1/M2-IN-1 / Unkown
HY-182059 GSTP1-IN-1 / Unkown
HY-RS05886 GSTP1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-W615446 GSTO1-IN-3 Inhibitor / Unkown
HY-167632 meso-Zeaxanthin 93.09% Unkown
HY-N11778 Bequinostatin C / Unkown
HY-RS16643 Gstp1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS23077 Gstp1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Gstp1 NCBI NCBI:2950