TNFAIP8 - TNF alpha induced protein 8 Gene

Homo sapiens

Also known as NDED; GG2-1; SCCS2; SCC-S2; MDC-3.13

Gene ID: 25816 | Gene type: protein coding

About TNFAIP8

Cytogenetic location: 5q23.1 Genomic coordinates (GRCh38): 5:119,268,759-119,399,688 (from NCBI)

This gene has 7 transcripts (splice variants), 131 orthologues and 3 paralogues. Broad expression in lymph node (RPKM 31.1), fat (RPKM 24.0) and 19 other tissues.

Summary

Enables cysteine-type endopeptidase inhibitor activity involved in apoptotic process. Involved in positive regulation of apoptotic process. Located in cytoplasm and nucleoplasm. [provided by Alliance of Genome Resources, Apr 2022]

TNFAIP8 Products(6)

mRNA	Protein	Name
NM_001077654.3	NP_001071122.1	tumor necrosis factor alpha-induced protein 8 isoform b
NM_001286813.2	NP_001273742.1	tumor necrosis factor alpha-induced protein 8 isoform a
NM_001286814.1	NP_001273743.1	tumor necrosis factor alpha-induced protein 8 isoform c
NM_001286815.2	NP_001273744.1	tumor necrosis factor alpha-induced protein 8 isoform d
NM_001286817.2	NP_001273746.1	tumor necrosis factor alpha-induced protein 8 isoform d
NM_014350.4	NP_055165.2	tumor necrosis factor alpha-induced protein 8 isoform a

TNFAIP8 Protein Structure

DUF758

0
100
198 a.a.

Protein Preferred Names

Protein Names

tumor necrosis factor alpha-induced protein 8

NF-kappa-B-inducible DED-containing protein

Recombinant TNFAIP8 Proteins

Cat. No.	Product Name	Accession	Purity
HY-P76682	TNFAIP8 Protein, Human (His)	O95379 (M1-I198)	≥95%

Related Diseases

Diseases

Alias

Plantar Fasciitis

Fasciitis, Plantar

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (4)

Cat. No.	Product Name	Purity	Rare Diseases
HY-RS14791	TNFAIP8 Human Pre-designed siRNA Set A	/	Unkown
HY-RS14792	TNFAIP8L1 Human Pre-designed siRNA Set A	/	Unkown
HY-RS14793	TNFAIP8L2 Human Pre-designed siRNA Set A	/	Unkown
HY-RS14794	TNFAIP8L3 Human Pre-designed siRNA Set A	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Rattus norvegicus	TNFAIP8	RGD	RGD:1305908
Felis catus	TNFAIP8	VGNC	VGNC:102349
Bos taurus	TNFAIP8	VGNC	VGNC:36157
Mus musculus	TNFAIP8	MGD	MGI:2147191
Macaca mulatta	TNFAIP8	VGNC	VGNC:79068
Canis familiaris	TNFAIP8	VGNC	VGNC:47652
Others	TNFAIP8	NCBI

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