Brs3 - bombesin receptor subtype 3 Gene

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 260319

About Brs3

Primary_assembly X: 134,906,784-134,930,983 forward strand.mRatBN7.2:CM026994.1

This gene has 1 transcript (splice variant), 125 orthologues, 14 paralogues and is associated with 9 phenotypes. Biased expression in Testes (RPKM 9.9), Brain (RPKM 2.) and 1 other tissue.

Summary

Predicted to enable G protein-coupled receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Located in neuron projection; neuronal cell body; and plasma membrane. Orthologous to human BRS3 (Bombesin Receptor subtype 3). [provided by Alliance of Genome Resources, Apr 2022]

Brs3 Products (1)

mRNA Protein Name
NM_152845.1 NP_690058.1 bombesin receptor subtype-3

Gene Ontology

  • Cellular Component
Cellular Component GO Annotation Evidence References Source
located in neuronal cell body IDA
IDA: Inferred from direct assay
12890504 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Brs3 Protein Structure

7tm_GPCRs

7tm_GPCRs: cl28897 (47 - 340)

7tm_GPCRs

7tm_GPCRs: cd14964 (49 - 73)

7tm_GPCRs

7tm_GPCRs: cd14964 (82 - 104)

7tm_GPCRs

7tm_GPCRs: cd14964 (120 - 142)

7tm_GPCRs

7tm_GPCRs: cd14964 (165 - 181)

7tm_GPCRs

7tm_GPCRs: cd14964 (214 - 237)

7tm_GPCRs

7tm_GPCRs: cd14964 (269 - 291)

7tm_GPCRs

7tm_GPCRs: cd14964 (308 - 333)

  • 0
  • 100
  • 200
  • 300
  • 399 a.a.
Protein Preferred Names Protein Names

bombesin receptor subtype-3

  • BRS-3

  • bombesin-like receptor 3

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (10)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-14342 MK-5046 Agonist 99.75% Unkown
HY-101844 ML-18 Antagonist 98.87% Unkown
HY-P1423A BA 1 TFA Agonist 99.35% Unkown
HY-14342A (R)-MK-5046 Control 98.21% Unkown
HY-18612 MK-7725 Agonist / Unkown
HY-P1423 BA 1 Agonist / Unkown
HY-RS01634 BRS3 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS01635 Brs3 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS01636 Brs3 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-W681071 BRS-3 receptor agonist-2 Agonist / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Brs3 NCBI NCBI:680