BRS3 - bombesin receptor subtype 3 Gene

Also Known as BB3; BB3R; BBR3

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 680

About BRS3

Cytogenetic location: Xq26.3 Genomic coordinates (GRCh38): X:136,487,947-136,493,780 (from NCBI)

This gene has 1 transcript (splice variant), 125 orthologues and 15 paralogues. Low expression observed in reference dataset.

Summary

The protein encoded by this gene is a G protein-coupled membrane receptor that binds bombesin-like peptides. This binding results in activation of a phosphatidylinositol-calcium second messenger system, with physiological effects including regulation of metabolic rate, glucose metabolism, and hypertension. [provided by RefSeq, Sep 2011]

BRS3 Products (1)

mRNA Protein Name
NM_001727.2 NP_001718.1 bombesin receptor subtype-3

BRS3 Protein Structure

7tm_1

7tm_1: 7 transmembrane receptor (rhodopsin family) (64 - 328)

  • 0
  • 100
  • 200
  • 300
  • 399 a.a.
Protein Preferred Names Protein Names

bombesin receptor subtype-3

  • BRS-3

  • G-protein coupled receptor

  • bombesin like receptor 3

Related Diseases

Diseases Alias
Jejunal Somatostatinoma

  • Jejunal Delta Cell Somatostatin Producing Tumor

  • Somatosatinoma Of Jejunum

  • Jejunal Somatostatin-Producing Neuroendocrine Tumor
Brugada Syndrome 4

  • BRGDA4

  • Brugada Syndrome, Type 4
Lung Cancer

  • Lung Carcinoma

  • Non-Small Cell Lung Carcinoma

  • Lung Cancer, Protection Against

  • Lung Cancer, Susceptibility To

  • Adenocarcinoma Of Lung, Somatic

  • Nonsmall Cell Lung Cancer

  • Adenocarcinoma Of Lung, Response To Tyrosine Kinase Inhibitor In

  • Lung Neoplasm

  • Carcinoma Of Lung

  • Lung Non-Small Cell Carcinoma

  • Non-Small Cell Lung Cancer

  • Nsclc

  • Lung Neoplasms

  • Malignant Neoplasm Of Lung

  • Alveolar Cell Carcinoma

  • Nonsmall Cell Lung Cancer, Somatic

  • Nonsmall Cell Lung Cancer, Response To Tyrosine Kinase Inhibitor In

  • Nonsmall Cell Lung Cancer, Susceptibility To

  • Lung Cancer, Somatic

  • Lung Cancer, Resistance To

  • Cancer Of Lung

  • Cancer Of Bronchus

  • Cancer Of The Lung

  • Lung Malignancies

  • Lung Malignant Tumors

  • Malignant Lung Tumor

  • Malignant Tumor Of Lung

  • Pulmonary Cancer

  • Pulmonary Carcinoma

  • Pulmonary Neoplasms

  • Respiratory Carcinoma

  • LNCR

  • Adenocarcinoma Of Lung

  • Neoplasm Of Lung

  • Cancer Lung

  • Carcinoma Non-Small Cell Lung

  • Carcinoma, Non-Small-Cell Lung

  • Lung Cancers

  • Lung Carcinomas

  • Cancer, Lung

  • Cancer, Lung, Non-Small Cell

  • Primary Malignant Neoplasm Of Lung

  • Bronchioloalveolar Adenocarcinoma
Brugada Syndrome

  • Sudden Unexpected Nocturnal Death Syndrome

  • Sudden Unexplained Nocturnal Death Syndrome

  • Bangungut

  • Brugada Type Idiopathic Ventricular Fibrillation

  • Pokkuri Death Syndrome

  • Sunds

  • Idiopathic Ventricular Fibrillation, Brugada Type

  • Sudden Unexplained Death

  • Dream Disease

  • Right Bundle Branch Block, St Segment Elevation, And Sudden Death Syndrome

  • Sudden Unexplained Death Syndrome

  • Suds

  • Sunds - [Sudden Unexplained Nocturnal Death Syndrome]
Body Mass Index Quantitative Trait Locus 11

  • OBESITY

  • Obesity, Susceptibility To

  • Leanness, Inherited

  • Obesity, Susceptibility To, Bmiq11

  • Obesity, Mild, Early-Onset

  • Obesity, Association With

  • Obesity, Early-Onset, Susceptibility To

  • Obesity, Severe

  • Obesity, Severe, And Type Ii Diabetes

  • Obesity, Late-Onset

  • BMIQ11

  • Obesity Bmiq11

  • Obesity, Early-Onset

  • Obesity , Susceptibility To

  • Simple Obesity Nos

  • Excess Fat

  • Obesity, Not Elsewhere Classified, Body Mass Index Not Elsewhere Classified

  • Adiposis
Fetal Hemoglobin Quantitative Trait Locus 1

  • Hereditary Persistence Of Fetal Hemoglobin

  • Delta-Beta-Thalassemia

  • Delta-Beta Thalassemia

  • Delta Beta-Thalassemia

  • HBFQTL1

  • Hemoglobin F, Hereditary Persistence Of

  • Hpfh

  • Hereditary Persistence Of Fetal Hemoglobin, Hb Gene Cluster-Related

  • Hemoglobin, Fetal, Quantitative Trait Locus 1

  • Hereditary Persistence Of Fetal Hemoglobin Thalassemia

  • Hpfh - [Hereditary Persistence Of Fetal Haemoglobin]

  • Fetal Haemoglobin

  • Persistence Of Fetal Haemoglobin

  • Persistent Haemoglobin F
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (10)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-14342 MK-5046 Agonist 99.75% Unkown
HY-101844 ML-18 Antagonist 98.87% Unkown
HY-P1423A BA 1 TFA Agonist 99.35% Unkown
HY-14342A (R)-MK-5046 Control 98.21% Unkown
HY-18612 MK-7725 Agonist / Unkown
HY-P1423 BA 1 Agonist / Unkown
HY-RS01634 BRS3 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS01635 Brs3 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS01636 Brs3 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-W681071 BRS-3 receptor agonist-2 Agonist / Unkown

Orthologs Information

Species Symbol Source ID
Felis catus BRS3 VGNC VGNC:60183
Canis familiaris BRS3 VGNC VGNC:38535
Mus musculus BRS3 MGD MGI:1100501
Rattus norvegicus BRS3 RGD RGD:628645
Bos taurus BRS3 VGNC VGNC:26574
Others BRS3 NCBI