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Cat. No.: HY-W010448R

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Imidazol-1-yl-acetic acid (Standard)

Name: Imidazol-1-yl-acetic acid (Standard)
Brand: MedChemExpress
SKU: HY-W010448R
Price: 35.00 USD
Availability: InStock
Rating: 5 (1 reviews)

Imidazol-1-yl-acetic acid (Standard) is the analytical standard of Imidazol-1-yl-acetic acid (HY-W010448). This product is intended for research and analytical applications. Imidazol-1-yl-acetic acid is a BRS-3 agonist that mediates anorectic effects through activation of orphan G protein-coupled receptors (Orphan GPCR) in peripheral tissues; it also serves as a green, water-soluble, recyclable bifunctional organocatalyst for transformations such as the Biginelli multicomponent reaction and epoxide ring opening. Imidazol-1-yl-acetic acid can be used for research on obesity.

For research use only. We do not sell to patients.

Purity : 98%
CAS No.: 22884-10-2
Formula: C₅H₆N₂O₂
Molecular Weight:126.11

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Imidazol-1-yl-acetic acid (Standard) Chemical Structure

CAS No.: 22884-10-2

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Application

The compound is the grade of analytical standard, which is the reference standard supplied assay. It is commonly used in qualitative, quantitative and methodological research experiments in HPLC, GC and MS.

Chemical Information

CAS No. 22884-10-2
Molecular Weight 126.11
Formula C₅H₆N₂O₂
SMILES

O=C(O)CN1C=CN=C1
Structure Classification
- Ketones, Aldehydes, Acids
Initial Source
- Endogenous metabolite
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

References

[1]. Kiyotsuka Y, et al. Synthesis and biological evaluation of novel imidazol-1-ylacetic acid derivatives as non-brain penetrant bombesin receptor subtype-3 (BRS-3) agonists. Bioorganic & medicinal chemistry letters. 2016 Sep 01;26(17):4205-10.

[2]. Singh SK, et al. Synthesis of imidazol-1-yl-acetic acid hydrochloride: a key intermediate for zoledronic acid. Beilstein journal of organic chemistry. 2008;4:42.

[3]. Simin Nazari, et al. Imidazol-1-yl-acetic acid as a novel green bifunctional organocatalyst for the synthesis of 1,8-dioxooctahydroxanthenes under solvent-free conditions, Chinese Chemical Letters, Volume 25, Issue 2, 2014, Pages 317-320, ISSN 1001-8417.

[4]. Mojgan Kargar, et al. Efficient and green synthesis of 3,4-dihydropyrimidin-2(1H)-ones/thiones using imidazol-1-yl-acetic acid as a novel, reusable and water-soluble organocatalyst, Catalysis Communications, Volume 15, Issue 1, 2011, Pages 123-126, ISSN 1566-7367.

[5]. Nazari S, et al. Imidazol-1-yl-acetic Acid as a Green Simple Bifunctional Organocatalyst for the Regioselective Conversion of Epoxides to 1, 2-azido Alcohols and β-hydroxythiocyanates[J]. Current Organocatalysis, 2014, 1(1): 7-12.

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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Imidazol-1-yl-acetic acid (Standard)

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Imidazol-1-yl-acetic acid (Standard)

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