Pfas - phosphoribosylformylglycinamidine synthase Gene

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 287420

Summary

Predicted to enable phosphoribosylformylglycinamidine synthase activity. Involved in glutamine metabolic process; response to xenobiotic stimulus; and ribonucleoside monophosphate biosynthetic process. Biomarker of hepatocellular carcinoma. Orthologous to human PFAS (phosphoribosylformylglycinamidine synthase). [provided by Alliance of Genome Resources, Apr 2022]

Pfas Products (1)

mRNA Protein Name
NM_001395097.1 NP_001382026.1 phosphoribosylformylglycinamidine synthase

Gene Ontology

  • Biological Process
Biological Process GO Annotation Evidence References Source
involved in glutamine metabolic process IDA
IDA: Inferred from direct assay
3436958 RGD
involved in response to xenobiotic stimulus IEP
IEP: Inferred from expression pattern
6206692 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

phosphoribosylformylglycinamidine synthase

  • FGAM synthetase

  • phosphoribosylformylglycinamidine synthase (FGAR amidotransferase)

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (15)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-DY3003 Tissue and Cell Fixative (4% Paraformaldehyde, PFA) / Unkown
HY-W792491 Perfluoropropanesulfonic acid 99.0% Unkown
HY-W142432 Perfluoroundecanoic acid Activator 99.85% Unkown
HY-W674169 Perfluorobutanesulfonamide 98.56% Unkown
HY-169848 (S)-Batylalcohol Inhibitor 99.86% Unkown
HY-21200 Perfluoroheptanesulfonic acid 97.7% Unkown
HY-115701 1-Stearoyl-2-15(S)-Hpete-Sn-Glycero-3-Pe Inducer 95.1% Unkown
HY-W080797 4,4,5,5,6,6,6-Heptafluorohexanoic acid 98.0% Unkown
HY-RS10357 PFAS Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-W142432S Perfluoroundecanoic acid-13C7 / Unkown
HY-181266 Antimalarial agent 55 Inhibitor / Unkown
HY-RS19931 Pfas Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS26433 Pfas Rat Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS28695 Fnta Rat Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-W679758 1H,1H,2H,2H-Perfluorodecanesulfonic acid / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Pfas NCBI NCBI:5198