AKR1B10 - Akr1b10 aldo-keto reductase family 1 member B10 Gene

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 296972

Summary

Enables NADP binding activity; alcohol dehydrogenase (NADP+) activity; and retinal binding activity. Involved in polyol metabolic process; retinal metabolic process; and retinol metabolic process. Located in cytosol. Orthologous to human AKR1B10 (aldo-keto reductase family 1 member B10). [provided by Alliance of Genome Resources, Apr 2022]

AKR1B10 Products (1)

mRNA Protein Name
NM_001013084.1 NP_001013102.1 aldo-keto reductase family 1 member B10

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence References Source
enables NADP+ binding IDA
IDA: Inferred from direct assay
20709016 RGD
enables NADPH binding IDA
IDA: Inferred from direct assay
20709016 RGD
enables aldose reductase (NADPH) activity IDA
IDA: Inferred from direct assay
20709016 RGD
enables all-trans-retinol dehydrogenase (NADP+) activity IDA
IDA: Inferred from direct assay
20709016 RGD
enables retinal binding IDA
IDA: Inferred from direct assay
20709016 RGD
Biological Process GO Annotation Evidence References Source
involved in polyol metabolic process IDA
IDA: Inferred from direct assay
20709016 RGD
involved in retinal metabolic process IDA
IDA: Inferred from direct assay
20709016 RGD
involved in retinol metabolic process IDA
IDA: Inferred from direct assay
20709016 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

aldo-keto reductase family 1 member B10

  • aldo-keto reductase family 1, member B10 (aldose reductase)

  • aldose reductase-related protein 1-like

Related Agents

  • Approval
  • Pre-clinical Phase

Approval

Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-105185 Fidarestat Inhibitor 99.63% Unkown

Pre-clinical Phase

Bioactive Molecules (8)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-139696 AKR1B10-IN-1 Inhibitor 99.08% Unkown
HY-W040265 Fenamic acid Inhibitor 98.25% Unkown
HY-RS00533 AKR1B10 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-185414 KB05-Biotin / Unkown
HY-168526 Keap1-Nrf2-IN-24 Inhibitor / Unkown
HY-122177 MK181 Inhibitor / Unkown
HY-RS17238 Akr1b10 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS23692 Akr1b10 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens AKR1B10 NCBI NCBI:57016