Hsp90aa1 - heat shock protein 90 alpha family class A member 1 Gene

Rattus norvegicus

Also known as Hsp86; Hsp90; Hspca

Gene ID: 299331 | Gene type: protein coding

About Hsp90aa1

Primary_assembly 6: 129,702,383-129,707,268 reverse strand.mRatBN7.2:CM026979.1

This gene has 1 transcript (splice variant), 271 orthologues, 11 paralogues and is associated with 17 phenotypes. Biased expression in Brain (RPKM 2165.3), Testes (RPKM 1934.7) and 9 other tissues.

Summary

Enables several functions, including Rho GDP-dissociation inhibitor binding activity; nucleotide binding activity; and sulfonylurea receptor binding activity. Involved in several processes, including cardiac muscle cell apoptotic process; positive regulation of lamellipodium assembly; and positive regulation of protein import into nucleus. Located in several cellular components, including basolateral plasma membrane; brush border membrane; and sperm mitochondrial sheath. Part of protein-containing complex. Biomarker of portal hypertension. Orthologous to human HSP90AA1 (heat shock protein 90 alpha family class A member 1). [provided by Alliance of Genome Resources, Apr 2022]

Hsp90aa1 Products(1)

mRNA	Protein	Name
NM_175761.2	NP_786937.1	heat shock protein HSP 90-alpha

Hsp90aa1 Protein Structure

PRK14083

0
200
400
600
733 a.a.

Protein Preferred Names

Protein Names

heat shock protein HSP 90-alpha

HSP 86	heat shock 86 kDa
heat shock protein 1, alpha	heat shock protein 86
heat shock protein 90, alpha (cytosolic), class A member 1	heat shock protein 90kDa alpha family class A member 1

Related Agents

Pre-clinical Phase

Bioactive Molecules (3)

Cat. No.	Product Name	Purity	Rare Diseases
HY-RS06415	HSP90AA1 Human Pre-designed siRNA Set A	/	Unkown
HY-RS06416	Hsp90aa1 Mouse Pre-designed siRNA Set A	/	Unkown
HY-RS06417	Hsp90aa1 Rat Pre-designed siRNA Set A	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Hsp90aa1	NCBI	NCBI:3320

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