Dyrk3 - dual specificity tyrosine phosphorylation regulated kinase 3 Gene
Species: Rattus norvegicus
About Dyrk3
This gene has 1 transcript (splice variant), 201 orthologues, 11 paralogues and is associated with 3 phenotypes. Biased expression in Testes (RPKM 172.1), Spleen (RPKM 69.1) and 4 other tissues.
Summary
Predicted to enable ATP binding activity; magnesium ion binding activity; and protein serine/threonine kinase activity. Predicted to be involved in several processes, including nuclear speck organization; protein phosphorylation; and regulation of intracellular signal transduction. Predicted to be located in several cellular components, including cytoplasmic stress granule; nuclear speck; and pericentriolar material. Predicted to be active in cytoplasm; cytoskeleton; and nucleus. Orthologous to human DYRK3 (dual specificity tyrosine phosphorylation regulated kinase 3). [provided by Alliance of Genome Resources, Apr 2022]
Dyrk3 Products (1)
| mRNA | Protein | Name |
|---|---|---|
| NM_001024767.1 | NP_001019938.1 | dual specificity tyrosine-phosphorylation-regulated kinase 3 |
Dyrk3 Protein Structure
PKc_DYRK2_3: cd14224 (141 - 520)
- 0
- 100
- 200
- 300
- 400
- 500
- 586 a.a.
| Protein Preferred Names | Protein Names | |
|---|---|---|
|
dual specificity tyrosine-phosphorylation-regulated kinase 3 |
|
Related Agents
- Clinical Phase
- Pre-clinical Phase
Clinical Phase
| Cat. No. | Product Name |
Effect
|
Purity |
Phase
|
|---|---|---|---|---|
| HY-105309 | GSK-626616 | Inhibitor | 99.88% | Phase 1 |
Pre-clinical Phase
| Cat. No. | Product Name |
Effect
|
Purity |
Rare Diseases
|
|---|---|---|---|---|
| HY-117049 | Leucettine L41 | Inhibitor | 98.98% | Unkown |
| HY-162750 | ZJCK-6-46 | Inhibitor | 99.06% | Unkown |
| HY-402805 | DYRK2-IN-2 | Inhibitor | / | Unkown |
| HY-402805A | DYRK2-IN-2 hydrochloride | Inhibitor | / | Unkown |
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