Sacs - sacsin molecular chaperone Gene

Also Known as RGD1305416

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 305940

Summary

Predicted to enable HSP70 protein binding activity; chaperone binding activity; and Proteasome binding activity. Predicted to be involved in negative regulation of inclusion body assembly. Predicted to be located in mitochondrion and nucleus. Human ortholog(s) of this gene implicated in Charlevoix-Saguenay spastic ataxia. Orthologous to human SACS (sacsin molecular chaperone). [provided by Alliance of Genome Resources, Apr 2022]

Sacs Products (10)

mRNA Protein Name
XM_006252167.4 XP_006252229.1 sacsin isoform X2
XM_039093901.1 XP_038949829.1 sacsin isoform X1
XM_039093903.1 XP_038949831.1 sacsin isoform X4
XM_039093907.1 XP_038949835.1 sacsin isoform X8
XM_039093906.1 XP_038949834.1 sacsin isoform X7
XM_039093908.1 XP_038949836.1 sacsin isoform X9
XM_039093909.1 XP_038949837.1 sacsin isoform X10
XM_006252168.4 XP_006252230.1 sacsin isoform X3
XM_039093904.1 XP_038949832.1 sacsin isoform X5
XM_039093905.1 XP_038949833.1 sacsin isoform X6
Protein Preferred Names Protein Names

sacsin

  • spastic ataxia of Charlevoix-Saguenay (sacsin)

Related Agents

  • Approval
  • Clinical Phase
  • Pre-clinical Phase

Approval

Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-128742 Thiamine monophosphate chloride dihydrate 99.24% Unkown

Clinical Phase

Bioactive Molecules (2)
Cat. No. Product Name Effect
Purity Phase
HY-14644 Apilimod Inhibitor 99.80% Phase 2
HY-14644A Apilimod mesylate Inhibitor 99.58% Phase 2

Pre-clinical Phase

Bioactive Molecules (22)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-P1410 GsMTx4 Inhibitor 99.89% Unkown
HY-P1410A GsMTx4 TFA Inhibitor 99.85% Unkown
HY-151798 TDI-11861 Inhibitor 99.35% Unkown
HY-132298 TDI-10229 Inhibitor 99.00% Unkown
HY-103194 KH7 Inhibitor 99.0% Unkown
HY-135960 BO-264 99.76% Unkown
HY-W001538 S-Propargylcysteine 97.0% Unkown
HY-100341 M2I-1 Inhibitor 98.0% Unkown
HY-130841 Apcin-A Inhibitor 98.0% Unkown
HY-118282 mPGES1-IN-7 Inhibitor 99.78% Unkown
HY-177531 S-Ac7-DOg 99.69% Unkown
HY-170868 CL2A-FL118 / Unkown
HY-110347 Mps1-IN-1 dihydrochloride Inhibitor / Unkown
HY-116709 Junenol / Unkown
HY-161287 HDAC6-IN-32 Inhibitor / Unkown
HY-164955 TTK/PLK1-IN-1 Inhibitor / Unkown
HY-E71103 (R)-Mandelonitrile oxidase / Unkown
HY-N10597 5'''-O-Feruloyl complanatoside B / Unkown
HY-N16371 6-Methoxy-8-hydroxyisocoumarin-3-carboxylic acid / Unkown
HY-RS12411 SACS Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-W127730 Pyridoxine 3,4-dipalmitate 99.99% Unkown
HY-W415799 (2S)-Ac4GalNAl / Unkown
Bioactive MoleculesInhibitory Antibodies (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-P992215 Anti-CD85a/LILRB3 Antibody (7C5) / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Sacs NCBI NCBI:26278