GKN1 - gastrokine 1 Gene

Homo sapiens

Also known as FOV; CA11; AMP18; BRICD1; foveolin

Gene ID: 56287 | Gene type: protein coding

About GKN1

Cytogenetic location: 2p13.3 Genomic coordinates (GRCh38): 2:68,974,636-68,980,976 (from NCBI)

This gene has 3 transcripts (splice variants), 126 orthologues and 2 paralogues. Restricted expression toward stomach (RPKM 11425.3).

Summary

The protein encoded by this gene is found to be down-regulated in human gastric Cancer tissue as compared to normal gastric mucosa. [provided by RefSeq, Jul 2008]

GKN1 Products(1)

mRNA	Protein	Name
NM_019617.4	NP_062563.4	gastrokine-1 precursor

GKN1 Protein Structure

BRICHOS

0
100
199 a.a.

Protein Preferred Names

Protein Names

gastrokine-1

18 kDa antrum mucosa protein

Recombinant GKN1 Proteins

Cat. No.	Product Name	Accession	Purity
HY-P76356	Gastrokine 1 Protein, Human (sf9, His)	Q9NS71 (N35-N199)	≥95%

Related Diseases

Diseases

Alias

Gastric Cancer

Stomach Cancer	Gastric Carcinoma
Stomach Carcinoma	Gastric Cancer, Somatic
Gastric Neoplasm	Carcinoma Of Stomach
Stomach Neoplasms	Malignant Neoplasm Of Stomach
Gastric Cancer Risk After H. Pylori Infection	Cancer Of The Stomach
Adult Stomach Cancer	Adult Stomach Carcinoma
GASC	Gastric Cancer Intestinal
Gastric Cancers	Gastric Carcinomas
Cancer, Gastric	Stomach Neoplasm
Malignant Neoplasm Of Body Of Stomach	Malignant Tumor Of Lesser Curve Of Stomach
Gastrocarcinoma Of Unspecified Site	Leather Bottle Stomach
Carcinoma Of Fundus Of Stomach	Cancer Of Fundus Of Stomach
Primary Malignant Neoplasm Of Body Of Stomach	Cancer Of Body Of Stomach
Primary Malignant Neoplasm Of Pyloric Antrum	Pyloric Antrum Cancer
Malignant Tumour Of Stomach

Granulomatous Disease, Chronic, Autosomal Recessive, 2

Chronic Granulomatous Disease Due To Deficiency Of Ncf-2	CGD2
Ncf2 Deficiency	P67-Phox Deficiency
Autosomal Recessive Chronic Granulomatous Disease Cytochrome B-Positive Type Ii	Granulomatous Disease, Chronic, Autosomal Recessive, Cytochrome B-Positive, Type 2
Granulomatous Disease, Chronic, Autosomal Recessive, Cytochrome B-Positive, Type Ii	Cgd, Autosomal Recessive Cytochrome B-Positive, Type Ii
Granulomatous Disease, Chronic, Due To Ncf2 Deficiency	Neutrophil Cytosol Factor 2 Deficiency
Chronic Granulomatous Disease 2, Autosomal Recessive	Autosomal Recessive Chronic Granulomatous Disease 2
Cdg2	Deficiency Of Ncf2
Deficiency Of P67-Phox	Chronic Granulomatous Disease Autosomal Recessive Cytochrome B-Positive Type Ii
Deficiency Of Neutrophil Cytosol Factor 2	Avellino Corneal Dystrophy

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS05461	GKN1 Human Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Canis familiaris	GKN1	VGNC	VGNC:41246
Mus musculus	GKN1	MGD	MGI:1913533
Bos taurus	GKN1	VGNC	VGNC:29388
Felis catus	GKN1	VGNC	VGNC:62570
Rattus norvegicus	GKN1	RGD	RGD:735014
Others	GKN1	NCBI