NPDC1 - neural proliferation, differentiation and control 1 Gene

Also Known as CAB; CAB-; CAB1; CAB-1; NPDC-1

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 56654

About NPDC1

Cytogenetic location: 9q34.3 Genomic coordinates (GRCh38): 9:137,039,463-137,046,177 (from NCBI)

This gene has 6 transcripts (splice variants) and 244 orthologues. Broad expression in prostate (RPKM 64.4), stomach (RPKM 34.1) and 22 other tissues.

Summary

Predicted to be located in plasma membrane. [provided by Alliance of Genome Resources, Apr 2022]

NPDC1 Products (1)

mRNA Protein Name
NM_015392.4 NP_056207.3 neural proliferation differentiation and control protein 1 precursor
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
16189514 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

NPDC1 Protein Structure

NPDC1

NPDC1: Neural proliferation differentiation control-1 protein (NPDC1) (1 - 325)

  • 0
  • 100
  • 200
  • 300
  • 325 a.a.
Protein Preferred Names Protein Names

neural proliferation differentiation and control protein 1

NPDC1 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
NPDC1 Q9NQX5 KRTAP10-8 Homo sapiens P60410 32296183
Intra
NPDC1 Q9NQX5 KRTAP10-8 Homo sapiens P60410 32296183
Intra
NPDC1 Q9NQX5 KRTAP10-9 Homo sapiens P60411 25416956
Intra
NPDC1 Q9NQX5 KRTAP10-9 Homo sapiens P60411 32296183
Intra
NPDC1 Q9NQX5 KRTAP10-9 Homo sapiens P60411 25416956
Intra
NPDC1 Q9NQX5 KRTAP10-9 Homo sapiens P60411 32296183
Intra
NPDC1 Q9NQX5 KRTAP10-5 Homo sapiens P60370 25416956
Intra
NPDC1 Q9NQX5 KRTAP10-7 Homo sapiens P60409 32296183
Intra
NPDC1 Q9NQX5 KRTAP10-7 Homo sapiens P60409 25416956
Intra
NPDC1 Q9NQX5 KRTAP10-7 Homo sapiens P60409 25416956
Intra
NPDC1 Q9NQX5 KRTAP10-7 Homo sapiens P60409 32296183
Intra
NPDC1 Q9NQX5 KRTAP10-7 Homo sapiens P60409 25416956
Intra
NPDC1 Q9NQX5 KRTAP12-2 Homo sapiens P59991 32296183
Intra
NPDC1 Q9NQX5 KRTAP12-2 Homo sapiens P59991 32296183
Intra
NPDC1 Q9NQX5 KRTAP9-3 Homo sapiens Q9BYQ3 32296183
Intra
NPDC1 Q9NQX5 KRTAP9-3 Homo sapiens Q9BYQ3 32296183
Intra
NPDC1 Q9NQX5 KRTAP1-3 Homo sapiens Q8IUG1 32296183
Intra
NPDC1 Q9NQX5 KRTAP1-3 Homo sapiens Q8IUG1 32296183
Intra
NPDC1 Q9NQX5 KRTAP12-3 Homo sapiens P60328 32296183
Intra
NPDC1 Q9NQX5 KRTAP12-3 Homo sapiens P60328 32296183
Intra
NPDC1 Q9NQX5 KRTAP4-4 Homo sapiens Q9BYR3 32296183
Intra
NPDC1 Q9NQX5 KRTAP4-4 Homo sapiens Q9BYR3 32296183
Intra
NPDC1 Q9NQX5 KRTAP1-1 Homo sapiens Q07627 32296183
Intra
NPDC1 Q9NQX5 KRTAP1-1 Homo sapiens Q07627 32296183
Intra
NPDC1 Q9NQX5 KRTAP10-6 Homo sapiens P60371 32296183
Intra
NPDC1 Q9NQX5 KRTAP10-6 Homo sapiens P60371 32296183
Intra
NPDC1 Q9NQX5 KRTAP2-4 Homo sapiens Q9BYR9 32296183
Intra
NPDC1 Q9NQX5 KRTAP2-4 Homo sapiens Q9BYR9 32296183
Intra
NPDC1 Q9NQX5 NOTCH2NLC Homo sapiens P0DPK4 32296183
Intra
NPDC1 Q9NQX5 NOTCH2NLC Homo sapiens P0DPK4 32296183
Intra
NPDC1 Q9NQX5 KRTAP4-1 Homo sapiens Q9BYQ7 32296183
Intra
NPDC1 Q9NQX5 KRTAP4-1 Homo sapiens Q9BYQ7 32296183
Intra
NPDC1 Q9NQX5 CYSRT1 Homo sapiens A8MQ03 32296183
Intra
NPDC1 Q9NQX5 CYSRT1 Homo sapiens A8MQ03 32296183
Intra
NPDC1 Q9NQX5 KRTAP5-9 Homo sapiens P26371 32296183
Intra
NPDC1 Q9NQX5 KRTAP5-9 Homo sapiens P26371 32296183
Intra
NPDC1 Q9NQX5 HNRNPK Homo sapiens P61978-2 32296183
Intra
NPDC1 Q9NQX5 HNRNPK Homo sapiens P61978-2 32296183
Intra
NPDC1 Q9NQX5 MDFI Homo sapiens Q99750 32296183
Intra
NPDC1 Q9NQX5 MDFI Homo sapiens Q99750 25416956
Intra
NPDC1 Q9NQX5 MDFI Homo sapiens Q99750 32296183
Intra
NPDC1 Q9NQX5 MDFI Homo sapiens Q99750 25416956
Intra
NPDC1 Q9NQX5 KHDRBS2 Homo sapiens Q5VWX1 25416956
Intra
NPDC1 Q9NQX5 KHDRBS2 Homo sapiens Q5VWX1 25416956
Intra
NPDC1 Q9NQX5 KHDRBS2 Homo sapiens Q5VWX1 32296183
Intra
NPDC1 Q9NQX5 KHDRBS2 Homo sapiens Q5VWX1 32296183
Intra
NPDC1 Q9NQX5 FHL5 Homo sapiens Q5TD97 32296183
Intra
NPDC1 Q9NQX5 FHL5 Homo sapiens Q5TD97 32296183
Intra
NPDC1 Q9NQX5 RBMY1F Homo sapiens Q15415 32296183
Intra
NPDC1 Q9NQX5 RBMY1F Homo sapiens Q15415 32296183
Intra
NPDC1 Q9NQX5 NOTCH2NLA Homo sapiens Q7Z3S9 25416956
Intra
NPDC1 Q9NQX5 NOTCH2NLA Homo sapiens Q7Z3S9 25416956
Intra
NPDC1 Q9NQX5 PILRA Homo sapiens Q9UKJ1
SPR
22396535
Cross: Cross-species interaction Intra: Intraspecies interaction

Recombinant NPDC1 Proteins

Cat. No. Product Name Accession Purity
HY-P71168 NPDC-1 Protein, Human (HEK293, His) Q9NQX5 (G35-D181) ≥ 95%, as determined by reducing SDS-PAGE.

Related Diseases

Diseases Alias
Gm1-Gangliosidosis, Type I
  • Gm1 Gangliosidosis Type 1

  • Beta-Galactosidase-1 Deficiency

  • Infantile Gm1 Gangliosidosis

  • GM1G1

  • Gangliosidosis, Generalized Gm1, Type 1

  • Glb1 Deficiency

  • Gangliosidosis Generalized Gm1 Type 1

  • Gangliosidosis, Generalized Gm1, Type I

  • Gangliosidosis, Generalized Gm1, Infantile Form

  • Beta Galactosidase Deficiency Type 1

  • Glb Deficiency Type 1

  • Gangliosidosis Generalized Gm1 Infantile Form

  • Norman-Landing Disease

  • Gm1-Gangliosidosis 1

  • Gangliosidosis Generalized Gm1 Infantile Type

  • Gm1-Gangliosidosis Infantile

  • Gangliosidosis Gm1 Infantile

  • Gangliosidosis, Gm1, Type I

  • Gangliosidosis Gm1

  • Beta-Galactosidase Deficiency

Schizophrenia 4
  • SCZD4

  • Schizophrenia, Susceptibility To, 4

  • Schizophrenia Susceptibility Locus, Chromosome 22q11-Related

  • Schizophrenia Susceptibility Locus Chromosome 22-Related

  • Schizophrenia, Type 4

Niemann-Pick Disease, Type A
  • Niemann-Pick Disease Type A

  • Sphingomyelin Lipidosis

  • Sphingomyelinase Deficiency

  • Niemann-Pick Disease, Intermediate, Protracted Neurovisceral

  • Acid Sphingomyelinase Deficiency, Neurovisceral Type

  • Asmd, Neurovisceral Type

  • Infantile Neurovisceral Acid Sphingomyelinase Deficiency

  • Infantile Neurovisceral Asmd

  • Npd-A

  • Niemann-Pick Disease A

  • NPDA

  • Classical Niemann-Pick Disease

  • Niemann-Pick Disease Acute Neuronopathic Form

  • Niemann-Pick Disease Acute Neurovisceral Form

  • Niemann-Pick Disease Classical Infantile Form

  • Niemann-Pick Disease Intermediate Protracted Neurovisceral

  • Niemann-Pick Disease Neuronopathic Type

  • Niemann-Pick Disease Type I

  • Npa

  • Niemann-Pick Diseases

Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Orthologs Information

Species Symbol Source ID
Felis catus NPDC1 VGNC VGNC:68530
Canis familiaris NPDC1 VGNC VGNC:43915
Macaca mulatta NPDC1 VGNC VGNC:75382
Bos taurus NPDC1 VGNC VGNC:55066
Rattus norvegicus NPDC1 RGD RGD:1303156
Mus musculus NPDC1 MGD MGI:1099802
Others NPDC1 NCBI