SDC4 - syndecan 4 Gene

Homo sapiens

Also known as SYND4

Gene ID: 6385 | Gene type: protein coding

About SDC4

Cytogenetic location: 20q13.12 Genomic coordinates (GRCh38): 20:45,325,288-45,348,424 (from NCBI)

This gene has 1 transcript (splice variant), 197 orthologues, 3 paralogues and is associated with 48 phenotypes. Broad expression in liver (RPKM 189.5), lung (RPKM 100.6) and 23 other tissues.

Summary

The protein encoded by this gene is a transmembrane (type I) heparan sulfate proteoglycan that functions as a receptor in intracellular signaling. The encoded protein is found as a homodimer and is a member of the syndecan proteoglycan family. This gene is found on chromosome 20, while a pseudogene has been found on chromosome 22. [provided by RefSeq, Jul 2008]

SDC4 Products(1)

mRNA	Protein	Name
NM_002999.4	NP_002990.2	syndecan-4 precursor

SDC4 Protein Structure

Syndecan

0
100
198 a.a.

Protein Preferred Names

Protein Names

syndecan-4

amphiglycan

Recombinant SDC4 Proteins

Cat. No.	Product Name	Accession	Purity
HY-P71927	Syndecan-4 Protein, Human	P31431 (E19-E145)	≥95%
HY-P73623	Syndecan-4 Protein, Human (HEK293, His)	P31431 (M1-E145)	≥95%

Related Diseases

Diseases

Alias

Thyroid Carcinoma

Thyroid Cancer	Malignant Neoplasm Of Thyroid
Thyroid Neoplasm

Achromatopsia 7

ACHM7

Achromatopsia, Type 7

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS12582	SDC4 Human Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Macaca mulatta	SDC4	VGNC	VGNC:98441
Canis familiaris	SDC4	VGNC	VGNC:45944
Mus musculus	SDC4	MGD	MGI:1349164
Rattus norvegicus	SDC4	RGD	RGD:3650
Bos taurus	SDC4	VGNC	VGNC:34381
Felis catus	SDC4	VGNC	VGNC:64946
Others	SDC4	NCBI