SDC3 - syndecan 3 Gene

Homo sapiens

Also known as SDCN; SYND3

Gene ID: 9672 | Gene type: protein coding

About SDC3

Cytogenetic location: 1p35.2 Genomic coordinates (GRCh38): 1:30,869,466-30,909,735 (from NCBI)

This gene has 4 transcripts (splice variants), 197 orthologues, 3 paralogues and is associated with 1 phenotype. Broad expression in brain (RPKM 64.6), spleen (RPKM 56.5) and 21 other tissues.

Summary

The protein encoded by this gene belongs to the syndecan proteoglycan family. It may play a role in the organization of cell shape by affecting the actin Cytoskeleton, possibly by transferring signals from the cell surface in a sugar-dependent mechanism. Allelic variants of this gene have been associated with obesity. [provided by RefSeq, Oct 2009]

SDC3 Products(1)

mRNA	Protein	Name
NM_014654.4	NP_055469.3	syndecan-3 precursor

SDC3 Protein Structure

Syndecan

0
100
200
300
400
442 a.a.

Protein Preferred Names

Protein Names

syndecan-3

N-syndecan

Recombinant SDC3 Proteins

Cat. No.	Product Name	Accession	Purity
HY-P73624	Syndecan-3 Protein, Human (HEK293, His)	ABM82826 (M1-K311)	≥95%

Related Diseases

Diseases

Alias

Body Mass Index Quantitative Trait Locus 11

OBESITY	Obesity, Susceptibility To
Leanness, Inherited	Obesity, Susceptibility To, Bmiq11
Obesity, Mild, Early-Onset	Obesity, Association With
Obesity, Early-Onset, Susceptibility To	Obesity, Severe
Obesity, Severe, And Type Ii Diabetes	Obesity, Late-Onset
Obesity , Susceptibility To	BMIQ11
Obesity Bmiq11	Obesity, Early-Onset
Simple Obesity Nos	Excess Fat
Obesity, Not Elsewhere Classified, Body Mass Index Not Elsewhere Classified	Adiposis

Alcohol-Induced Mental Disorder

Psychoses, Alcoholic

Muscular Dystrophy

Muscular Dystrophies	Congenital Md
Congenital Muscular Dystrophy	Cmd
Mdc	Dystrophy, Muscular
Gower'S Muscular Dystrophy	Progressive Musclular Dystrophy
Pseudohypertrophic Atrophy	Pseudohypertrophic Muscle Paralysis
Pseudohypertrophic Muscular Atrophy	Pseudohypertrophic Muscular Dystrophy
Pseudohypertrophic Paralysis	Pseudomuscular Hypertrophy

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS12581	SDC3 Human Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Mus musculus	SDC3	MGD	MGI:1349163
Macaca mulatta	SDC3	VGNC	VGNC:76999
Bos taurus	SDC3	VGNC	VGNC:34380
Canis familiaris	SDC3	VGNC	VGNC:45943
Felis catus	SDC3	VGNC	VGNC:64945
Rattus norvegicus	SDC3	RGD	RGD:621486
Others	SDC3	NCBI