Aqp3 - aquaporin 3 (Gill blood group) Gene

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 65133

Summary

Enables glycerol channel activity and water channel activity. Involved in glycerol transport and water transport. Located in basolateral plasma membrane. Biomarker of brain ischemia and hypothyroidism. Orthologous to human AQP3 (Aquaporin 3 (Gill blood group)). [provided by Alliance of Genome Resources, Apr 2022]

Aqp3 Products (1)

mRNA Protein Name
NM_031703.2 NP_113891.2 aquaporin-3

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables glycerol channel activity IDA
IDA: Inferred from direct assay
7517548 RGD
enables polyol transmembrane transporter activity IDA
IDA: Inferred from direct assay
9733774 RGD
enables water channel activity IDA
IDA: Inferred from direct assay
7517548 RGD
Biological Process GO Annotation Evidence References Source
involved in glycerol transmembrane transport IDA
IDA: Inferred from direct assay
7517548 RGD
involved in polyol transmembrane transport IDA
IDA: Inferred from direct assay
9733774 RGD
involved in water transport IDA
IDA: Inferred from direct assay
7517548 RGD
Cellular Component GO Annotation Evidence References Source
located in basolateral plasma membrane IDA
IDA: Inferred from direct assay
7517548 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

aquaporin-3

  • 31.4 kDa water channel protein

  • AQP-3

  • aquaglyceroporin-3

Related Agents

  • Approval
  • Pre-clinical Phase

Approval

Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-B0557 Bisacodyl Inhibitor 99.71% Yes

Pre-clinical Phase

Bioactive Molecules (6)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-126073 DFP00173 99.46% Unkown
HY-126074 Z433927330 98.20% Unkown
HY-RS00875 AQP3 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-157979 AQP3-IN-1 Inhibitor / Unkown
HY-RS17446 Aqp3 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS23902 Aqp3 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Aqp3 NCBI NCBI:360