Cnpy3 - canopy FGF signaling regulator 3 Gene

Also Known as CAG4A; ERDA5; Tnrc5; PRAT4A; 1600025D17Rik; 2410050O22Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 72029

Summary

This gene encodes a member of the canopy family of proteins. The encoded protein may play a role in the maturation of toll-like receptors. Homozygous knockout mice for this gene show reduced cell surface expression of toll-like receptors and an impaired immune response including reduced production of cytokines in a mouse model of sepsis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2015]

Cnpy3 Products (4)

mRNA Protein Name
NM_001305988.1 NP_001292917.1 protein canopy homolog 3 isoform 2 precursor
NM_001305989.1 NP_001292918.1 protein canopy homolog 3 isoform 3
NM_001305990.1 NP_001292919.1 protein canopy homolog 3 isoform 3
NM_028065.4 NP_082341.1 protein canopy homolog 3 isoform 1 precursor

Gene Ontology

  • Molecular Function
Molecular Function GO Annotation Evidence References Source
enables signaling receptor binding IPI
IPI: Inferred from physical interaction
16338228 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

protein canopy homolog 3

  • canopy 3 homolog

  • protein associated with Tlr4

  • protein associated with toll-like receptor 4

  • trinucleotide repeat-containing gene 5 protein

Recombinant Cnpy3 Proteins

Cat. No. Product Name Accession Purity
HY-P76273 CNPY3/PRAT4A Protein, Mouse (HEK293, Fc) Q9DAU1-1 (A27-P272) ≥ 90%, as determined by reducing SDS-PAGE.
HY-P76274 CNPY3/PRAT4A Protein, Mouse (HEK293, His) Q9DAU1-1 (A27-P272) ≥ 85%, as determined by reducing SDS-PAGE.

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS02912 CNPY3 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS18655 Cnpy3 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS25141 Cnpy3 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Cnpy3 NCBI NCBI:10695