PPIG - peptidylprolyl isomerase G Gene
Also Known as CYP; SRCyp; SCAF10; CARS-Cyp
Species: Homo sapiens
About PPIG
This gene has 22 transcripts (splice variants), 205 orthologues and 22 paralogues. Ubiquitous expression in thyroid (RPKM 12.9), endometrium (RPKM 11.6) and 25 other tissues.
Summary
Enables cyclosporin A binding activity and peptidyl-prolyl cis-trans isomerase activity. Involved in protein peptidyl-prolyl isomerization. Located in cytosol and nuclear speck. [provided by Alliance of Genome Resources, Apr 2022]
PPIG Products (1)
| mRNA | Protein | Name |
|---|---|---|
| NM_004792.3 | NP_004783.2 | peptidyl-prolyl cis-trans isomerase G |
| Molecular Function GO Annotation | Evidence | References | Source |
|---|---|---|---|
| enables peptidyl-prolyl cis-trans isomerase activity |
IDA
IDA: Inferred from direct assay
|
20676357 | GOA |
| enables protein binding |
IPI
IPI: Inferred from physical interaction
|
21516116 | GOA |
PPIG Protein Structure
Pro_isomerase: Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD (12 - 175)
- 0
- 200
- 400
- 600
- 754 a.a.
| Protein Preferred Names | Protein Names | |
|---|---|---|
|
peptidyl-prolyl cis-trans isomerase G |
|
PPIG Protein-protein interaction Information
|
Type
|
Protein Name | Protein ID | Interactor | Interactor Species | Interactor ID | Detection Method | References |
|---|---|---|---|---|---|---|---|
|
Intra
|
PPIG | Q13427 | BEND7 | Homo sapiens | Q8N7W2-2 | 25416956 | |
|
Intra
|
PPIG | Q13427 | DACH1 | Homo sapiens | Q9UI36-2 | 25416956 | |
|
Intra
|
PPIG | Q13427 | DACH1 | Homo sapiens | Q9UI36-2 | 25416956 | |
|
Intra
|
PPIG | Q13427 | LGALS3 | Homo sapiens | Q6NVH9 | 25416956 | |
|
Intra
|
PPIG | Q13427 | LGALS3 | Homo sapiens | Q6NVH9 | 25416956 | |
|
Intra
|
PPIG | Q13427 | LGALS3 | Homo sapiens | Q6NVH9 | 25416956 | |
|
Cross
|
PPIG | Q13427 | P0C6X7-PRO_0000037309 | Human SARS coronavirus | P0C6X7-PRO_0000037309 | 22046132 | |
|
Cross
|
PPIG | Q13427 | P0C6X7-PRO_0000037309 | Human SARS coronavirus | P0C6X7-PRO_0000037309 | 22046132 | |
|
Intra
|
PPIG | Q13427 | PNMA2 | Homo sapiens | Q9UL42 | 25416956 | |
|
Intra
|
PPIG | Q13427 | PNMA2 | Homo sapiens | Q9UL42 | 25416956 | |
|
Intra
|
PPIG | Q13427 | RBM39 | Homo sapiens | Q14498 | 25416956 | |
|
Intra
|
PPIG | Q13427 | SMN1 | Homo sapiens | Q16637 | 25416956 | |
|
Intra
|
PPIG | Q13427 | SMN1 | Homo sapiens | Q16637 | 21516116 | |
|
Intra
|
PPIG | Q13427 | TFCP2 | Homo sapiens | Q12800 | 25416956 | |
|
Intra
|
PPIG | Q13427 | PPCDC | Homo sapiens | Q96CD2 | 25416956 | |
|
Intra
|
PPIG | Q13427 | CEP70 | Homo sapiens | Q8NHQ1 | 25416956 | |
|
Intra
|
PPIG | Q13427 | THAP1 | Homo sapiens | Q9NVV9 | 25416956 | |
|
Intra
|
PPIG | Q13427 | THAP1 | Homo sapiens | Q9NVV9 | 25416956 | |
|
Intra
|
PPIG | Q13427 | PCBP1 | Homo sapiens | Q15365 | 22365833 |
Related Diseases
| Diseases | Alias | |
|---|---|---|
| Coumarin Resistance |
|
|
| Epilepsy, Idiopathic Generalized 11 |
|
|
| Liver Disease |
|
|
| Hemorrhagic Cystitis |
|
|
| Epilepsy, Idiopathic Generalized 10 |
|
|
| Chronic Venous Insufficiency |
|
|
| Heart Disease |
|
|
| Neurotic Excoriation |
|
|
| Diarrhea |
|
|
| Exudative Vitreoretinopathy 1 |
|
|
| Neonatal Abstinence Syndrome |
|
|
| Severe Cutaneous Adverse Reaction |
|
|
| Disease By Infectious Agent |
|
|
| Tobacco Addiction |
|
|
| Anxiety |
|
|
| Invasive Aspergillosis |
|
|
| Hypertrophy Of Tongue Papillae |
|
|
| Mycobacterium Tuberculosis 1 |
|
|
| Myocardial Infarction |
|
|
| Gilbert Syndrome |
|
|
| Conidiobolomycosis |
|
|
| Epilepsy |
|
|
| Bilirubin Metabolic Disorder |
|
|
| Major Depressive Disorder |
|
|
| Acute Frontal Sinusitis |
|
|
| Outlet Dysfunction Constipation |
|
|
| Pulmonary Disease, Chronic Obstructive |
|
|
| Schizophrenia |
|
|
| Rete Ovarii Benign Neoplasm |
|
|
| Rete Ovarii Adenoma |
|
|
| Glucosephosphate Dehydrogenase Deficiency |
|
|
| Hypertension, Essential |
|
|
| Lennox-Gastaut Syndrome |
|
|
| Lipoid Congenital Adrenal Hyperplasia |
|
|
| Crigler-Najjar Syndrome, Type I |
|
|
| Constipation |
|
|
| Stroke, Ischemic |
|
|
| Body Mass Index Quantitative Trait Locus 11 |
|
|
| Migraine With Or Without Aura 1 |
|
|
| Myopathy |
|
|
| Alzheimer Disease, Familial, 1 |
|
|
| Attention Deficit-Hyperactivity Disorder |
|
|
| Nervous System Disease |
|
|
Orthologs Information
| Species | Symbol | Source | ID |
|---|---|---|---|
| Rattus norvegicus | PPIG | RGD | RGD:620315 |
| Felis catus | PPIG | VGNC | VGNC:107604 |
| Bos taurus | PPIG | VGNC | VGNC:33199 |
| Canis familiaris | PPIG | VGNC | VGNC:44853 |
| Macaca mulatta | PPIG | VGNC | VGNC:81511 |
| Mus musculus | PPIG | MGD | MGI:2445173 |
| Others | PPIG | NCBI |