Glutarimide-(1-oxoisoindoline-5-carbaldehyde)
Based on 1 Customer Validation
Glutarimide-(1-oxoisoindoline-5-carbaldehyde) is an E3 ubiquitin ligase cereblon (CRBN) ligand used to recruit the cereblon protein. Glutarimide-(1-oxoisoindoline-5-carbaldehyde) can be linked to a target protein ligand via a linker to form a PROTAC.
For research use only. We do not sell to patients.
- Purity: ≥97.0%
- CAS No.: 2582979-82-4
- Formula: C14H12N2O4
- Molecular Weight:272.26
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Storage:
4°C, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)
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Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
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Help & FAQs
Biological Activity
Description
IC50 & Target
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Cereblon |
In Vitro
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 2582979-82-4
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Appearance Solid
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Molecular Weight 272.26
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Formula C14H12N2O4
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SMILES
O=CC1=CC=C2C(=O)N(CC2=C1)C3C(=O)NC(=O)CC3
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
4°C, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)
Purity & Documentation
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Data Sheet (241 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Glutarimide-(1-oxoisoindoline-5-carbaldehyde) Related Classifications
HY-W452760 Related Classifications
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