Glutathione oxidized disodium (Synonyms: L-Glutathione oxidized disodium; GSSG disodium; Oxiglutatione disodium)

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Glutathione oxidized disodium is produced by the oxidation of glutathione which is a major intracellular antioxidant and detoxifying agent.

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CAS No. : 103239-24-3

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Other In-stock Forms of Glutathione oxidized disodium:

Glutathione oxidized

Other Forms of Glutathione oxidized disodium:

Glutathione oxidized In-stock

8 Publications Citing Use of MCE Glutathione oxidized disodium

Cell Proliferation/Viability Assay

RT-PCR

In Vivo Efficacy Study

: Glutathione oxidized disodium purchased from MedChemExpress. Usage Cited in: Chem Biol Interact. 2024 Dec 31:111368. [Abstract]; DFO (100 μM，24 h) and GSH (2 mM, 24 h) reversed the inhibition of Sal on MGC803 cell viability.

: Glutathione oxidized disodium purchased from MedChemExpress. Usage Cited in: Invest Ophthalmol Vis Sci. 2025 May 1;66(5):19. [Abstract]; The fluorescence intensity of MMP-2 in the HFSFs treated with glutathione oxidized (GLU, 2.48 mg/mL, 24 h) was 2.09 times greater than that in the HFSFs treated with ARP-100 (ARP, 100 μM, 24 h).

: Glutathione oxidized disodium purchased from MedChemExpress. Usage Cited in: Invest Ophthalmol Vis Sci. 2025 May 1;66(5):19. [Abstract]; The MMP-2 mRNA level in the HFSFs treated with glutathione oxidized (GLU, 2.48 mg/mL, 24 h) was 2.46 times greater than that in the ARP-100 (ARP, 100 μM, 24 h)-treated HFSFs.

: Glutathione oxidized disodium purchased from MedChemExpress. Usage Cited in: Invest Ophthalmol Vis Sci. 2025 May 1;66(5):19. [Abstract]; IF analysis revealed a notable increase in collagen I fluorescence intensity in the HFSFs treated with ARP-100 (ARP, 100 μM, 24 h), whereas a reduction in collagen I fluorescence intensity was found in HFSFs treated with glutathione oxidized (GLU, 2.48 mg/mL, 24 h).

: Glutathione oxidized disodium purchased from MedChemExpress. Usage Cited in: Invest Ophthalmol Vis Sci. 2025 May 1;66(5):19. [Abstract]; WB analysis of MMP-2 and collagen I expression in HFSFs following treatment with ARP-100 (ARP, 100 μM), glutathione oxidized (GLU, 2.48 mg/mL), or PBS for 24 hours.

: Glutathione oxidized disodium purchased from MedChemExpress. Usage Cited in: Invest Ophthalmol Vis Sci. 2025 May 1;66(5):19. [Abstract]; Compared with guinea pigs receiving periocular injections of vehicle (5 mM, 10 μL on days 1, 4, 7, 10, and 13 over two weeks), those treated with glutathione oxidized (Glu, 20 mg/mL, 10 μL on the same schedule) exhibited a 1.76-fold increase in relative myopia, along with a 1.78-fold increase in axial length (AL).

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Description

Glutathione oxidized disodium is produced by the oxidation of glutathione which is a major intracellular antioxidant and detoxifying agent^[1].

IC₅₀ & Target

Human Endogenous Metabolite

Molecular Weight

656.59

Formula

C₂₀H₃₀N₆Na₂O₁₂S₂

CAS No.

103239-24-3

Structure Classification

Others

Initial Source

Endogenous metabolite

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Handling Instructions (2659 KB)

References

[1]. Nur E, et al. Increased efflux of oxidized glutathione (GSSG) causes glutathione depletion and potentially diminishes antioxidant defense in sickle erythrocytes. Biochim Biophys Acta. 2011 Nov;1812(11):1412-7. [Content Brief]

Glutathione oxidized disodium Related Classifications

Metabolic Disease

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The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass		Concentration		Volume		Molecular Weight *
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The dilution calculator equation

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)	×	Volume _(start)	=	Concentration _(final)	×	Volume _(final)
	×		=		×
C1		V1		C2		V2

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Glutathione oxidized disodium103239-24-3L-Glutathione oxidized disodium GSSG disodium Oxiglutatione disodiumEndogenous MetaboliteReactive Oxygen Species (ROS)antioxidantdetoxifyingInhibitorinhibitorinhibit

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