Glycerol-3-phosphate oxidase, E. coli
Based on 2 publication(s) in Google Scholar
Glycerol-3-phosphate oxidase, E. coli (GPO) is a key intermediate in glycerol metabolism. Glycerol-3-phosphate oxidase, E. coli is the skeleton of phospholipids in membrane lipids, and also a substrate in the respiratory chain. Glycerol-3-phosphate oxidase, E. coli produces electrons through oxidation. Glycerol-3-phosphate oxidase, E. coli is an enzyme with important functions in the field of biochemistry, and is widely used in medical testing and scientific research.
For research use only. We do not sell to patients.
- CAS No.: 9046-28-0
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
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Publications Citing Use of MedChemExpress (MCE) Glycerol-3-phosphate oxidase, E. coli
MoreAll Endogenous Metabolite Isoforms
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Biological Activity
Glycerol-3-phosphate oxidase, E. coli catalyzes the oxidation of glycerol 3-phosphate to dihydroxyacetone phosphate (DHAP), accompanied by the reduction of O2 to H2O2. Hydrogen peroxide generated by this enzyme is critical for the cytotoxicity of Mycoplasma pneumoniae against host cells. It participates in glycerol metabolism and is indispensable for glycerol utilization[2].
Glycerol-3-phosphate oxidase, E. coli can utilize glyceraldehyde 3-phosphate (GAP), a glycolytic intermediate, as a substrate, though the structure of its catalytic product remains uncharacterized. Accordingly, this enzyme may produce hydrogen peroxide in mycoplasma infection when glycerol is unavailable[3].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
| NCT Number | Sponsor | Condition | Start Date |
Phase
|
|---|---|---|---|---|
| NCT01329991 | Plexxikon| | 2011-05 | PHASE1 |
1.1.3.21
≥25 U/mg protein
One unit will oxidize 1.0 μmole of L-glycerol 3-phosphate to dihydroxyacetone phosphate with the formation of H2O2 per min at 37°C, at the appropriate pH 7.0.
Chemical Information
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CAS No. 9046-28-0
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Appearance Solid
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Color Light yellow to yellow
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SMILES
[Glycerol-3-phosphate oxidase, E. coli]
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Synonyms
GPO
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Publications (2)
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Journal Impact Factor
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Most Recent
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ACS Synth Biol
Autonomous Synthesis and Scrambling of Phospholipids, Linked to Recycling of Cofactors in Synthetic Cells. [Abstract]2026 Mar 18. PMID: 41849276 -
J Orthop Surg Res
Functional mechanism and clinical implications of miR-455-5p in delayed fracture healing. [Abstract]2025 Oct 29;20(1):943. PMID: 41163026
Solvent & Solubility
H2O : 1 mg/mL (Need ultrasonic)
Purity & Documentation
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Data Sheet (268 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Handling Instructions (2659 KB)
References
[1]. Koga Y, et al. Anaerobic glycerol-3-phosphate dehydrogenase complex from hyperthermophilic archaeon Thermococcus kodakarensis KOD1. J Biosci Bioeng. 2019;127(6):679-685. [Content Brief]
[2]. Hames C, et al. Glycerol metabolism is important for cytotoxicity of Mycoplasma pneumoniae. J Bacteriol. 2009 Feb;191(3):747-53. [Content Brief]
[3]. Maenpuen S, et al. Kinetic mechanism of L-α-glycerophosphate oxidase from Mycoplasma pneumoniae. FEBS J. 2015 Aug;282(16):3043-59. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Glycerol-3-phosphate oxidase, E. coli Related Classifications
HY-P2733 Related Classifications
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