Guanidino ethyl disulfide
Guanidino ethyl disulfide (GED) (Compound 23) is a NO Synthase (NOS) inhibitor with EC50s of 110, 630 and 180 μM for iNOS, eNOS and bNOS, respectivly. Guanidino ethyl disulfide effectively inhibits nitrite production in J774.2 macrophages. Guanidino ethyl disulfide can be used for circulatory shock, inflammation and neurological diseases research.
For research use only. We do not sell to patients.
- CAS No.: 1072-13-5
- Formula: C6H16N6S2
- Molecular Weight:236.36
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
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iNOS 110 μM (EC50) |
eNOS 630 μM (EC50) |
bNOS 180 μM (EC50) |
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| Macrophage | IC50 |
7.4 μM
Compound: GED
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Inhibition of LPS-induced NO production in ddY mouse macrophages after 20 hrs by Griess reagent assay
Inhibition of LPS-induced NO production in ddY mouse macrophages after 20 hrs by Griess reagent assay
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[PMID: 15270564] |
Chemical Information
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CAS No. 1072-13-5
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Molecular Weight 236.36
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Formula C6H16N6S2
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SMILES
N=C(NCCSSCCNC(N)=N)N
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Guanidino ethyl disulfide Related Classifications
HY-176779 Related Classifications
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