HIV-1 inhibitor-36
HIV-1 inhibitor-36 (Compound 2) is a potent HIV-1. HIV-1 inhibitor-36 has the potential for further development as novel latency reversing agents.
For research use only. We do not sell to patients.
- CAS No.: 2170506-18-8
- Formula: C14H14Cl2N2O2S
- Molecular Weight:345.24
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| HEK293 | CC50 |
>20 μM
Compound: 99
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Cytotoxicity against HEK293 cells assessed as reduction in cell growth incubated for 48 hrs by MTS assay
Cytotoxicity against HEK293 cells assessed as reduction in cell growth incubated for 48 hrs by MTS assay
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[PMID: 30973727] |
| HEK293 | EC50 |
>40 μM
Compound: 99
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Activation of non-specific gene expression in HEK293- FlpIn-FM cells harboring LTR driven CBR reporter co-expressing CMV driven CBG reporter assessed as CMV driven gene expression incubated for 48 hr using Chroma-Glo substrate by luciferase dual reporter
Activation of non-specific gene expression in HEK293- FlpIn-FM cells harboring LTR driven CBR reporter co-expressing CMV driven CBG reporter assessed as CMV driven gene expression incubated for 48 hr using Chroma-Glo substrate by luciferase dual reporter
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[PMID: 30973727] |
| HepG2 | CC50 |
4.4 μM
Compound: 2
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Cytotoxicity against human HepG2 cells assessed as growth incubation incubated for 48 hrs by cell titer glo assay
Cytotoxicity against human HepG2 cells assessed as growth incubation incubated for 48 hrs by cell titer glo assay
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[PMID: 32251744] |
| HepG2 | CC50 |
4.4 μM
Compound: 99
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Cytotoxicity against human HepG2 cells assessed as reduction in cell growth incubated for 48 hrs by CellTiter-Glo assay
Cytotoxicity against human HepG2 cells assessed as reduction in cell growth incubated for 48 hrs by CellTiter-Glo assay
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[PMID: 30973727] |
Chemical Information
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CAS No. 2170506-18-8
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Molecular Weight 345.24
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Formula C14H14Cl2N2O2S
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SMILES
CC1=CC(OCCCC(NC2=NC=C(S2)Cl)=O)=CC=C1Cl
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
HIV-1 inhibitor-36 Related Classifications
HY-147553 Related Classifications
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