HIV-1 inhibitor-74
HIV-1 inhibitor-74 (compound 10c) is a potent HIV-1 inhibitor with an EC50 value of 0.0047 µM for HIV-1 IIIB. HIV-1 inhibitor-74 shows cytotoxicity. HIV-1 inhibitor-74 inhibits WT HIV-1 RT activity with an IC50 value of 0.134 µM. HIV-1 inhibitor-74 shows broad-spectrum anti HIV-1 activity.
For research use only. We do not sell to patients.
- Formula: C28H31N9O2S
- Molecular Weight:557.67
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
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HIV-1 (WT) 0.134 μM (IC50) |
HIV (IIIB) 0.0047 μM (EC50) |
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| MT4 | CC50 |
18.74 μM
Compound: 10c
|
Cytotoxicity against human MT4 cells assessed as reduction in cell viability incubated for 5 days by MTT method
Cytotoxicity against human MT4 cells assessed as reduction in cell viability incubated for 5 days by MTT method
|
[PMID: 39167895] |
Chemical Information
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Molecular Weight 557.67
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Formula C28H31N9O2S
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SMILES
N#C/C=C/C1=CC(C)=C(OC2=C(C=CS3)C3=NC(NC4CCN(CC5=CN(CC(NC)=O)N=N5)CC4)=N2)C(C)=C1
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)