HIV-1 ligand-1
HIV-1 ligand-1 (IIA-5) is a PROTAC target protein ligand. HIV-1 ligand-1 can be used for the synthesis of PROTAC HIV-1 degrader-1 (HY-187361).
For research use only. We do not sell to patients.
- CAS No.: 3107740-50-8
- Formula: C27H21ClF3N3O4
- Molecular Weight:543.92
-
Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Description
IC50 & Target
[1]|
HIV-1IIIB |
HIV-1 NL4-3 |
In Vitro
Binding of the ligand to the target protein causes the PROTAC to attach to the target protein, leading to ubiquitination and subsequent degradation.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
-
CAS No. 3107740-50-8
-
Molecular Weight 543.92
-
Formula C27H21ClF3N3O4
-
SMILES
O=C(O)C1=CC(N(C)C([C@@H](NC(CC2=CNC3=C2C=C(F)C=C3)=O)CC4=CC(F)=CC(F)=C4)=O)=CC=C1Cl
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)