2. PROTAC
  3. Ligands for E3 Ligase
  4. Hydrouracil-4-benzazimide-7-NH2

Hydrouracil-4-benzazimide-7-NH2 is an E3 ubiquitin ligase cereblon (CRBN) ligand used to recruit the cereblon protein. Hydrouracil-4-benzazimide-7-NH2 can be linked to a target protein ligand via a linker to form a PROTAC.

Nos produits utilisent uniquement pour la recherche. Nous ne vendons pas aux patients.

Hydrouracil-4-benzazimide-7-NH2

Hydrouracil-4-benzazimide-7-NH2 Chemical Structure

CAS No. : 2250288-89-0

Size Stock
50 mg   Obtenir un devis  
100 mg   Obtenir un devis  
250 mg   Obtenir un devis  

* Veuillez sélectionner la quantité avant d'ajouter des articles.

This product is a controlled substance and not for sale in your territory.

Hydrouracil-4-benzazimide-7-NH2 Related Antibodies

Top Publications Citing Use of Products

Voir tous les produits spécifiques à Isoform Ligands for E3 Ligase:

Voir toutes les isoformes
von Hippel-Lindau (VHL) MDM2 Cereblon IAP KLHDC2 Fbxo3 RNF4 DCAF11 SPOP DCAF1 UHRF1 TRIM21 NEURL1B KLHL41 RNF114 DDB1 FEM1B

  • Activité biologique

  • Pureté et documentation

  • Avis client

Description

Hydrouracil-4-benzazimide-7-NH2 is an E3 ubiquitin ligase cereblon (CRBN) ligand used to recruit the cereblon protein. Hydrouracil-4-benzazimide-7-NH2 can be linked to a target protein ligand via a linker to form a PROTAC.

IC50 & Target

Cereblon

 

In Vitro

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Hydrouracil-4-benzazimide-7-NH2 Related Antibodies
Masse moléculaire

273.25

Formule

C12H11N5O3
CAS No.
SMILES

O=C1NC(=O)C(N2N=NC=3C=C(N)C=CC3C2=O)CC1
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
  • No file chosen (Maximum size is: 1024 Kb)
  • If you have published this work, please enter the PubMed ID.
  • Your name will appear on the site.

Hydrouracil-4-benzazimide-7-NH2 Related Classifications

  • Calculateur de molarité

  • Calculateur de dilution

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Hydrouracil-4-benzazimide-7-NH22250288-89-0Ligands for E3 LigaseE3 ligase-recruiting MoietyInhibitorinhibitorinhibit

Vos produits récemment consultés:

Demande en ligne

Your information is safe with us. * Required Fields.

Nom du produit

  

Requested Quantity *

Nom du demandeur *

 

Civilité

Adresse e-mail *

 

Numéro de téléphone *

Department

 

Nom de l'organisation *

City

État

Country or Region *

      

Remarques

Bulk Inquiry

Inquiry Information

Nom du produit:
Hydrouracil-4-benzazimide-7-NH2
Cat. No.:
HY-W999669
Quantité:
MCE Japan Authorized Agent:

Avis client

Thank You for Your Feedback!

Request for HNMR Report

Please fill out this form to request the QC report. We will send it to your Email address shortly.

Your information is safe with us. * Required Fields.

Nom du produit

  

Lot #

Nom du demandeur *

 

Adresse e-mail *

Numéro de téléphone

 

Department *

Nom de l'organisation *

 

Country or Region *

Remarques

SAFETY DATA SHEET (SDS)

Request for HNMR Report

We have received your request and will respond to you as soon as possible.