(+)-Coclaurine
(+)-Coclaurine ((+)-(R)-Coclaurine), benzyltetrahydroisoquinoline alkaloid isolated from a variety of plant sources. (+)-Coclaurine has anti-aging activity.
For research use only. We do not sell to patients.
- CAS No.: 2196-60-3
- Formula: C17H19NO3
- Molecular Weight:285.34
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| H9 | EC50 |
0.8 μg/mL
Compound: R-coclaurine
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Inhibition of HIV replication in H9 cells
Inhibition of HIV replication in H9 cells
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[PMID: 18316190] |
| H9 | EC50 |
2.8 μM
Compound: 121
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Antiviral activity against HIV1 3B infected in H9 cells assessed as inhibition of viral replication by p24 antigen ELISA
Antiviral activity against HIV1 3B infected in H9 cells assessed as inhibition of viral replication by p24 antigen ELISA
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[PMID: 20187635] |
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 2196-60-3
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Molecular Weight 285.34
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Formula C17H19NO3
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SMILES
OC(C=C1)=CC=C1C[C@@H]2C3=CC(O)=C(OC)C=C3CCN2
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Synonyms
(+)-(R)-Coclaurine; (R)-Coclaurine; d-Coclaurine
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Structure Classification
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Initial Source
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Siva S Panda, et al. Protective effects of Aporosa octandra bark extract against D-galactose induced cognitive impairment and oxidative stress in mice. Heliyon. 2018 Nov 30;4(11):e00951. [Content Brief]
[2]. H Watanabe, et al. Effects of d-coclaurine and d-reticuline, benzyltetrahydroisoquinoline alkaloids, on levels of 3,4-dihydroxyphenylacetic acid and homovanillic acid in the mouse striatum. J Pharmacobiodyn. 1983 Oct;6(10):793-6. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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