IDH1 Inhibitor 7-d2
Based on 1 Customer Validation
IDH1 Inhibitor 7-d2 is the deuterium labeled IDH1 Inhibitor 7 (HY-150238). IDH1 Inhibitor 7 is an IDH1 inhibitor with an IC50 of less than 100 nM.
For research use only. We do not sell to patients.
- Purity: 99.93%
- CAS No.: 2135309-51-0
- Formula: C22H22D2F3N7O
- Molecular Weight:461.48
-
Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
Biological Activity
-
Chemical Information
-
Solvent & Solubility
- Purity & Documentation
- References
-
Help & FAQs
Biological Activity
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Chemical Information
-
CAS No. 2135309-51-0
-
Unlabeled Cas 2135309-56-5
-
Appearance Solid
-
Molecular Weight 461.48
-
Formula C22H22D2F3N7O
-
Color White to off-white
-
SMILES
O=C1NC([2H])([2H])[C@H](C(C)C)N1C2=NC(N[C@H](C3=CN(C4=CC=C(C(F)(F)F)C=C4)C=N3)C)=NC=C2
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
DMSO : 100 mg/mL (216.69 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
-
Data Sheet (271 KB)
-
SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
-
Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.1669 mL | 10.8347 mL | 21.6694 mL | 54.1735 mL |
| 5 mM | 0.4334 mL | 2.1669 mL | 4.3339 mL | 10.8347 mL | |
| 10 mM | 0.2167 mL | 1.0835 mL | 2.1669 mL | 5.4174 mL | |
| 15 mM | 0.1445 mL | 0.7223 mL | 1.4446 mL | 3.6116 mL | |
| 20 mM | 0.1083 mL | 0.5417 mL | 1.0835 mL | 2.7087 mL | |
| 25 mM | 0.0867 mL | 0.4334 mL | 0.8668 mL | 2.1669 mL | |
| 30 mM | 0.0722 mL | 0.3612 mL | 0.7223 mL | 1.8058 mL | |
| 40 mM | 0.0542 mL | 0.2709 mL | 0.5417 mL | 1.3543 mL | |
| 50 mM | 0.0433 mL | 0.2167 mL | 0.4334 mL | 1.0835 mL | |
| 60 mM | 0.0361 mL | 0.1806 mL | 0.3612 mL | 0.9029 mL | |
| 80 mM | 0.0271 mL | 0.1354 mL | 0.2709 mL | 0.6772 mL | |
| 100 mM | 0.0217 mL | 0.1083 mL | 0.2167 mL | 0.5417 mL |
IDH1 Inhibitor 7-d2 Related Classifications
HY-150238S Related Classifications
Powered by Bioz