IKZF2-degrader 1
IKZF2-degrader 1 (Compound 31) is a IKZF2 molecular glue degrader, with an DC50 of 0.5 nM. IKZF2-degrader 1 has minimal CK1α degradation activity relatively (DC50: 210 nM). IKZF2-degrader 1 can be used for research of IKZF2-dependent cancers.
For research use only. We do not sell to patients.
- CAS No.: 2983840-43-1
- Formula: C27H30FN7O3
- Molecular Weight:519.57
-
Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
|
IZKF2 0.5 nM (DC50) |
Chemical Information
-
CAS No. 2983840-43-1
-
Molecular Weight 519.57
-
Formula C27H30FN7O3
-
SMILES
CC(C)NC1=NNC2=C(CN3CCCC3)C=C(C4=C(F)C(CN(C5CCC(NC5=O)=O)C6=O)=C6C=C4)N=C21
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)