NAMPT ligand-1
NAMPT ligand-1 is a ligand targeting NAMPT, consisting of a NAMPT-binding domain, a linker, and a maleimide-fused enediyne warhead with a cyclopropane-modified alkyne terminus. NAMPT ligand-1 can be used to synthesize PROTEC NAMPT Degrader-1 (HY-189001). NAMPT ligand-1 induces the degradation of NAMPT via proximity-induced radical oxidation, and this process is independent of endogenous proteolytic mechanisms. NAMPT ligand-1 can be used in ovarian cancer research.
For research use only. We do not sell to patients.
- Formula: C30H41NO4
- Molecular Weight:479.65
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Description
Chemical Information
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Molecular Weight 479.65
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Formula C30H41NO4
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SMILES
O=C(O)CCCCCN1C(C(C#CC(C2CC2)CCCC)=C(C#CC(C3CC3)CCCC)C1=O)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
NAMPT ligand-1 Related Classifications
HY-188123 Related Classifications
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