1. Immunology/Inflammation
  2. NO Synthase
  3. iNOS inhibitor-10

iNOS inhibitor-10 is an iNOS inhibitor (IC50: 65 nM). iNOS inhibitor-10 has antiproliferative effect against triple negative breast cancer cells.

For research use only. We do not sell to patients.

iNOS inhibitor-10 Chemical Structure

iNOS inhibitor-10 Chemical Structure

CAS No. : 2918773-63-2

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iNOS inhibitor-10 is an iNOS inhibitor (IC50: 65 nM). iNOS inhibitor-10 has antiproliferative effect against triple negative breast cancer cells[1].

IC50 & Target[1]


0.065 μM (IC50)


>50 μM (IC50)

In Vitro

iNOS inhibitor-10 (Compound 1b, 1 μM) inhibits iNOS activity by 83%, and is inactive against eNOS[1].
iNOS inhibitor-10 (0.001-100 μM, 5 days) reduces cell viability of MDA-MB-231 cells[1].
iNOS inhibitor-10 (25 μM, 24 h) prevents migration of MDA-MB-231 cells[1].
iNOS inhibitor-10 (measured in liver microsomes) shows a reasonably metabolic stability, with a t1/2 of 38 min CLint of 39.6 mL/min/Kg[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Cell Viability Assay[1]

Cell Line: MDA-MB-231
Concentration: 0.001-100 μM
Incubation Time: 5 days
Result: Inhibited cell viability with an EC50 value of 24.71 μM.
Molecular Weight




Unlabeled CAS




Room temperature in continental US; may vary elsewhere.


Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation
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iNOS inhibitor-10 Related Classifications

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    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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