Integrase-LEDGF/p75 allosteric inhibitor 1
Integrase-LEDGF/p75 allosteric inhibitor 1 (Compound 31h) is an orally active integrase-LEDGF/p75 (IN-LEDGF/p75) allosteric inhibitor. Integrase-LEDGF/p75 allosteric inhibitor 1 inhibits HIV-1 DNA integration and shows antiviral activity with an EC50 of 3.9 nM against HIV-1 recombinant molecular clone NL432.
For research use only. We do not sell to patients.
- CAS No.: 1431738-14-5
- Formula: C33H41NO6S
- Molecular Weight:579.75
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
EC50: 3.9 nM (NL432)[1]
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| MT4 | CC50 |
24 μM
Compound: 31h
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Cytotoxicity against human MT4 cells assessed as reduction in cell viability measured after 4 days by MTT assay
Cytotoxicity against human MT4 cells assessed as reduction in cell viability measured after 4 days by MTT assay
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[PMID: 32773094] |
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 1431738-14-5
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Molecular Weight 579.75
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Formula C33H41NO6S
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SMILES
CC1=CC=C(C=C1C)C2=C(C(C3=CC=C4OCCCC4=C3C)=C(C(C)=C2NS(C)(=O)=O)C(C(O)=O)OC(C)(C)C)C
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Integrase-LEDGF/p75 allosteric inhibitor 1 Related Classifications
HY-147653 Related Classifications
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