JAK1/TYK2-IN-5
JAK1/TYK2-IN-5 (compound A1) is a JAK1/TYK2 inhibitor with Ki values of 0.0044 nM, 0.02 nM, 6.9 μM, 0.79 μM, 0.21 μM and 0.55 μM for TYK2 JH2, JAK1 JH2, JAK1 JH1, JAK2 JH1, JAK3 JH1 and TYK2 JH1, respectiverly. JAK1/TYK2-IN-5 inhibts IFNα induced TYK2/JAK1-mediated STAT activation.
For research use only. We do not sell to patients.
- CAS No.: 3026367-07-4
- Formula: C26H30N7O4P
- Molecular Weight:535.53
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
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TYK2 JH1 0.0044 nM (Kd) |
JAK1 JH2 0.02 nM (Kd) |
Chemical Information
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CAS No. 3026367-07-4
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Molecular Weight 535.53
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Formula C26H30N7O4P
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SMILES
O=C(C1=NN=C(NC(C2CC2)=O)C=C1NC3=CC=CC(C4=NN(C)C(P(C5CC5)(C6CC6)=O)=C4)=C3OC)N
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)