Sos2 - SOS Ras/Rho guanine nucleotide exchange factor 2 Gene

Also Known as SOS-2; mSOS-2

Species: Mus musculus

Gene Type: protein coding
Gene ID: 20663

Summary

Enables guanyl-nucleotide exchange factor activity. Acts upstream of or within several processes, including B cell homeostasis; regulation of T cell activation; and regulation of pro-B cell differentiation. Is expressed in several structures, including genitourinary system; hemolymphoid system gland; intestine; liver; and lung. Human ortholog(s) of this gene implicated in Noonan syndrome 9. Orthologous to human SOS2 (SOS Ras/Rho guanine nucleotide exchange factor 2). [provided by Alliance of Genome Resources, Apr 2022]

Sos2 Products (1)

mRNA Protein Name
NM_001135559.1 NP_001129031.1 son of sevenless homolog 2
Protein Preferred Names Protein Names

son of sevenless homolog 2

Sos2 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
Sos2 Q02384 Grb2 Mus musculus Q60631
Anti Bait CoIP
15953601
Intra
Sos2 Q02384 Abi1 Mus musculus Q8CBW3
Y2H
11003655
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (8)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-145737A PROTAC SOS1 degrader-1 TFA 98.38% Unkown
HY-145737 PROTAC SOS1 degrader-1 / Unkown
HY-161173 PROTAC SOS1 degrader-5 / Unkown
HY-168480 SOS2 ligand 1 Ligand / Unkown
HY-184855 (S,S,S,S)-AHPC-Me / Unkown
HY-RS13577 SOS2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS19958 Sos2 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS26460 Sos2 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Sos2 NCBI NCBI:6655